| Full name: interleukin 36 gamma | Alias Symbol: IL-1H1|IL-1RP2|IL-1F9|IL1H1|IL1E | ||
| Type: protein-coding gene | Cytoband: 2q14.1 | ||
| Entrez ID: 56300 | HGNC ID: HGNC:15741 | Ensembl Gene: ENSG00000136688 | OMIM ID: 605542 |
| Drug and gene relationship at DGIdb | |||
Expression of IL36G:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IL36G | 56300 | 220322_at | 2.5283 | 0.3469 | |
| GSE20347 | IL36G | 56300 | 220322_at | 1.5853 | 0.0279 | |
| GSE23400 | IL36G | 56300 | 220322_at | 0.8538 | 0.0018 | |
| GSE26886 | IL36G | 56300 | 220322_at | -1.2723 | 0.1101 | |
| GSE29001 | IL36G | 56300 | 220322_at | 0.4965 | 0.5319 | |
| GSE38129 | IL36G | 56300 | 220322_at | 1.6382 | 0.0029 | |
| GSE45670 | IL36G | 56300 | 220322_at | 4.2686 | 0.0000 | |
| GSE53622 | IL36G | 56300 | 54429 | 1.5843 | 0.0006 | |
| GSE53624 | IL36G | 56300 | 54429 | 0.7332 | 0.0107 | |
| GSE63941 | IL36G | 56300 | 220322_at | 0.3703 | 0.5996 | |
| GSE77861 | IL36G | 56300 | 220322_at | 2.6138 | 0.0291 | |
| GSE97050 | IL36G | 56300 | A_23_P17053 | 1.0253 | 0.1657 | |
| SRP064894 | IL36G | 56300 | RNAseq | 1.1639 | 0.0683 | |
| SRP133303 | IL36G | 56300 | RNAseq | 3.1139 | 0.0001 | |
| SRP159526 | IL36G | 56300 | RNAseq | 1.2249 | 0.2625 | |
| SRP219564 | IL36G | 56300 | RNAseq | 1.8451 | 0.2264 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by IL36G expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of IL36G:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IL36G | 56300 | 6 | 2 | 22 | |
| GSE20123 | IL36G | 56300 | 6 | 2 | 22 | |
| GSE43470 | IL36G | 56300 | 3 | 1 | 39 | |
| GSE46452 | IL36G | 56300 | 1 | 4 | 54 | |
| GSE47630 | IL36G | 56300 | 7 | 0 | 33 | |
| GSE54993 | IL36G | 56300 | 0 | 6 | 64 | |
| GSE54994 | IL36G | 56300 | 10 | 0 | 43 | |
| GSE60625 | IL36G | 56300 | 0 | 3 | 8 | |
| GSE74703 | IL36G | 56300 | 3 | 1 | 32 | |
| GSE74704 | IL36G | 56300 | 3 | 2 | 15 | |
| TCGA | IL36G | 56300 | 31 | 6 | 59 |
Total number of gains: 70; Total number of losses: 27; Total Number of normals: 391.
Somatic mutations of IL36G:
Generating mutation plots.
Highly correlated genes for IL36G:
Showing top 20/529 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IL36G | S100A7A | 0.752184 | 4 | 0 | 4 |
| IL36G | BLACAT1 | 0.738472 | 3 | 0 | 3 |
| IL36G | SPRR2G | 0.734711 | 7 | 0 | 7 |
| IL36G | HEPHL1 | 0.729117 | 3 | 0 | 3 |
| IL36G | MMP14 | 0.71665 | 3 | 0 | 3 |
| IL36G | PSPH | 0.712803 | 3 | 0 | 3 |
| IL36G | SPRR4 | 0.703707 | 4 | 0 | 4 |
| IL36G | PIGX | 0.692537 | 4 | 0 | 3 |
| IL36G | TRAF7 | 0.690378 | 4 | 0 | 3 |
| IL36G | CCL20 | 0.685579 | 11 | 0 | 10 |
| IL36G | ALOXE3 | 0.68205 | 7 | 0 | 6 |
| IL36G | CEACAM19 | 0.67998 | 7 | 0 | 7 |
| IL36G | HAS3 | 0.674837 | 6 | 0 | 5 |
| IL36G | ANLN | 0.674316 | 5 | 0 | 5 |
| IL36G | HMMR | 0.674065 | 5 | 0 | 4 |
| IL36G | CDC6 | 0.673881 | 4 | 0 | 3 |
| IL36G | KRTDAP | 0.669404 | 7 | 0 | 5 |
| IL36G | FMNL2 | 0.668968 | 4 | 0 | 4 |
| IL36G | CKAP2L | 0.667432 | 5 | 0 | 5 |
| IL36G | NDUFAF7 | 0.667377 | 3 | 0 | 3 |
For details and further investigation, click here
