IFNE

 

Full name: interferon epsilon Alias Symbol: IFNE1
Type: protein-coding gene Cytoband: 9p21.3
Entrez ID: 338376 HGNC ID: HGNC:18163 Ensembl Gene: ENSG00000184995 OMIM ID: 615223
Drug and gene relationship at DGIdb

 

IFNE involved pathways:

KEGG pathway Description View
hsa04630Jak-STAT signaling pathway

 

Expression of IFNE:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 IFNE 338376 1553574_at -0.1504 0.7425
GSE26886 IFNE 338376 1553574_at 0.1213 0.3092
GSE45670 IFNE 338376 1553574_at 1.3035 0.0049
GSE53622 IFNE 338376 122683 0.3212 0.2675
GSE53624 IFNE 338376 122683 0.3107 0.2431
GSE63941 IFNE 338376 1553574_at -0.2600 0.6164
GSE77861 IFNE 338376 1553574_at 0.0445 0.8633
GSE97050 IFNE 338376 A_23_P302060 0.4017 0.4352
TCGA IFNE 338376 RNAseq 0.1770 0.7432

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by IFNE expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of IFNE:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 IFNE 338376 2 17 11
GSE20123 IFNE 338376 2 17 11
GSE43470 IFNE 338376 3 13 27
GSE46452 IFNE 338376 2 24 33
GSE47630 IFNE 338376 3 27 10
GSE54993 IFNE 338376 7 2 61
GSE54994 IFNE 338376 8 17 28
GSE60625 IFNE 338376 3 0 8
GSE74703 IFNE 338376 3 10 23
GSE74704 IFNE 338376 0 13 7
TCGA IFNE 338376 11 53 32

Total number of gains: 44; Total number of losses: 193; Total Number of normals: 251.  

 

Somatic mutations of IFNE:

 

Generating mutation plots.

 

Highly correlated genes for IFNE:

 

Showing all 9 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
IFNEMIR31HG0.786473706
IFNEONECUT30.681773303
IFNECREG20.632861303
IFNEONECUT20.600797303
IFNESUGCT0.556521303
IFNEDPEP10.554665303
IFNEHMMR-AS10.553972303
IFNESPRR2G0.532634403
IFNEZNF7780.521223403

For details and further investigation, click here