| Full name: small proline rich protein 2G | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 1q21.3 | ||
| Entrez ID: 6706 | HGNC ID: HGNC:11267 | Ensembl Gene: ENSG00000159516 | OMIM ID: 617590 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SPRR2G:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPRR2G | 6706 | 236119_s_at | 1.9747 | 0.3107 | |
| GSE26886 | SPRR2G | 6706 | 236119_s_at | -0.1898 | 0.7827 | |
| GSE45670 | SPRR2G | 6706 | 236119_s_at | 3.7951 | 0.0000 | |
| GSE53622 | SPRR2G | 6706 | 5084 | 0.8954 | 0.0955 | |
| GSE53624 | SPRR2G | 6706 | 5084 | 0.3976 | 0.3084 | |
| GSE63941 | SPRR2G | 6706 | 236119_s_at | 0.1321 | 0.6718 | |
| GSE77861 | SPRR2G | 6706 | 236119_s_at | 1.6244 | 0.0093 | |
| GSE97050 | SPRR2G | 6706 | A_33_P3334423 | 1.0372 | 0.1159 | |
| SRP159526 | SPRR2G | 6706 | RNAseq | 1.6943 | 0.3626 | |
| TCGA | SPRR2G | 6706 | RNAseq | 1.8648 | 0.0030 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by SPRR2G expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPRR2G:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPRR2G | 6706 | 15 | 0 | 15 | |
| GSE20123 | SPRR2G | 6706 | 15 | 0 | 15 | |
| GSE43470 | SPRR2G | 6706 | 6 | 2 | 35 | |
| GSE46452 | SPRR2G | 6706 | 2 | 1 | 56 | |
| GSE47630 | SPRR2G | 6706 | 15 | 0 | 25 | |
| GSE54993 | SPRR2G | 6706 | 0 | 4 | 66 | |
| GSE54994 | SPRR2G | 6706 | 16 | 0 | 37 | |
| GSE60625 | SPRR2G | 6706 | 0 | 0 | 11 | |
| GSE74703 | SPRR2G | 6706 | 6 | 1 | 29 | |
| GSE74704 | SPRR2G | 6706 | 7 | 0 | 13 | |
| TCGA | SPRR2G | 6706 | 39 | 2 | 55 |
Total number of gains: 121; Total number of losses: 10; Total Number of normals: 357.
Somatic mutations of SPRR2G:
Generating mutation plots.
Highly correlated genes for SPRR2G:
Showing top 20/376 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPRR2G | MYH9 | 0.787699 | 3 | 0 | 3 |
| SPRR2G | XPR1 | 0.787473 | 3 | 0 | 3 |
| SPRR2G | RBP1 | 0.776682 | 3 | 0 | 3 |
| SPRR2G | WDR54 | 0.776382 | 3 | 0 | 3 |
| SPRR2G | SEMA4F | 0.761325 | 3 | 0 | 3 |
| SPRR2G | ADAM17 | 0.760276 | 3 | 0 | 3 |
| SPRR2G | ALOXE3 | 0.755645 | 8 | 0 | 7 |
| SPRR2G | GLA | 0.752885 | 3 | 0 | 3 |
| SPRR2G | PDPN | 0.751135 | 3 | 0 | 3 |
| SPRR2G | TPX2 | 0.750097 | 3 | 0 | 3 |
| SPRR2G | SNX10 | 0.747367 | 3 | 0 | 3 |
| SPRR2G | TRAF7 | 0.742167 | 3 | 0 | 3 |
| SPRR2G | SPRY4 | 0.741554 | 3 | 0 | 3 |
| SPRR2G | TTYH3 | 0.735173 | 3 | 0 | 3 |
| SPRR2G | IL36G | 0.734711 | 7 | 0 | 7 |
| SPRR2G | PRR9 | 0.731572 | 7 | 0 | 7 |
| SPRR2G | LRRC59 | 0.730724 | 3 | 0 | 3 |
| SPRR2G | MSANTD3 | 0.730606 | 3 | 0 | 3 |
| SPRR2G | KRTDAP | 0.726801 | 8 | 0 | 8 |
| SPRR2G | BLACAT1 | 0.726763 | 3 | 0 | 3 |
For details and further investigation, click here
