| Full name: one cut homeobox 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 390874 | HGNC ID: HGNC:13399 | Ensembl Gene: | OMIM ID: 611294 |
| Drug and gene relationship at DGIdb | |||
Expression of ONECUT3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ONECUT3 | 390874 | 234109_x_at | -0.1098 | 0.5953 | |
| GSE26886 | ONECUT3 | 390874 | 234109_x_at | -0.0186 | 0.9182 | |
| GSE45670 | ONECUT3 | 390874 | 234109_x_at | 0.0307 | 0.8562 | |
| GSE63941 | ONECUT3 | 390874 | 234109_x_at | 0.1484 | 0.3509 | |
| GSE77861 | ONECUT3 | 390874 | 234109_x_at | -0.3087 | 0.0696 | |
| GSE97050 | ONECUT3 | 390874 | A_33_P3238969 | 0.6174 | 0.1956 | |
| SRP007169 | ONECUT3 | 390874 | RNAseq | 0.7560 | 0.4356 | |
| SRP064894 | ONECUT3 | 390874 | RNAseq | 0.6509 | 0.0217 | |
| SRP133303 | ONECUT3 | 390874 | RNAseq | 0.4494 | 0.0285 | |
| SRP159526 | ONECUT3 | 390874 | RNAseq | 0.5147 | 0.3393 | |
| SRP193095 | ONECUT3 | 390874 | RNAseq | -0.0169 | 0.9234 | |
| SRP219564 | ONECUT3 | 390874 | RNAseq | 2.3267 | 0.0008 | |
| TCGA | ONECUT3 | 390874 | RNAseq | -2.8004 | 0.0329 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by ONECUT3 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ONECUT3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ONECUT3 | 390874 | 4 | 6 | 20 | |
| GSE20123 | ONECUT3 | 390874 | 4 | 5 | 21 | |
| GSE43470 | ONECUT3 | 390874 | 1 | 10 | 32 | |
| GSE46452 | ONECUT3 | 390874 | 47 | 1 | 11 | |
| GSE47630 | ONECUT3 | 390874 | 5 | 7 | 28 | |
| GSE54993 | ONECUT3 | 390874 | 16 | 3 | 51 | |
| GSE54994 | ONECUT3 | 390874 | 8 | 15 | 30 | |
| GSE60625 | ONECUT3 | 390874 | 9 | 0 | 2 | |
| GSE74703 | ONECUT3 | 390874 | 1 | 7 | 28 | |
| GSE74704 | ONECUT3 | 390874 | 3 | 3 | 14 | |
| TCGA | ONECUT3 | 390874 | 6 | 25 | 65 |
Total number of gains: 104; Total number of losses: 82; Total Number of normals: 302.
Somatic mutations of ONECUT3:
Generating mutation plots.
Highly correlated genes for ONECUT3:
Showing top 20/94 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ONECUT3 | NKX6-3 | 0.759684 | 3 | 0 | 3 |
| ONECUT3 | PIWIL2 | 0.727349 | 3 | 0 | 3 |
| ONECUT3 | ALDH3B1 | 0.708164 | 3 | 0 | 3 |
| ONECUT3 | IFNE | 0.681773 | 3 | 0 | 3 |
| ONECUT3 | DLK2 | 0.675789 | 3 | 0 | 3 |
| ONECUT3 | ALK | 0.670769 | 3 | 0 | 3 |
| ONECUT3 | RAD52 | 0.6698 | 3 | 0 | 3 |
| ONECUT3 | TERT | 0.642351 | 3 | 0 | 3 |
| ONECUT3 | CARD6 | 0.635507 | 3 | 0 | 3 |
| ONECUT3 | APOA4 | 0.634223 | 3 | 0 | 3 |
| ONECUT3 | CLCN1 | 0.632398 | 4 | 0 | 4 |
| ONECUT3 | CXCR3 | 0.628038 | 4 | 0 | 4 |
| ONECUT3 | KLK4 | 0.626048 | 3 | 0 | 3 |
| ONECUT3 | KRT36 | 0.622375 | 3 | 0 | 3 |
| ONECUT3 | DSPP | 0.621156 | 4 | 0 | 4 |
| ONECUT3 | ARHGAP30 | 0.620822 | 4 | 0 | 3 |
| ONECUT3 | IPPK | 0.620798 | 3 | 0 | 3 |
| ONECUT3 | SERPINB3 | 0.61484 | 3 | 0 | 3 |
| ONECUT3 | NBEAL2 | 0.614145 | 4 | 0 | 3 |
| ONECUT3 | BCL2L10 | 0.613091 | 4 | 0 | 3 |
For details and further investigation, click here
