| Full name: metallothionein 1B | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16q13 | ||
| Entrez ID: 4490 | HGNC ID: HGNC:7394 | Ensembl Gene: ENSG00000169688 | OMIM ID: 156349 |
| Drug and gene relationship at DGIdb | |||
Expression of MT1B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | MT1B | 4490 | 44902 | -0.4756 | 0.0005 | |
| GSE53624 | MT1B | 4490 | 44902 | -0.1486 | 0.1491 | |
| GSE97050 | MT1B | 4490 | A_23_P37983 | -0.2195 | 0.6299 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MT1B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MT1B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MT1B | 4490 | 5 | 0 | 25 | |
| GSE20123 | MT1B | 4490 | 5 | 1 | 24 | |
| GSE43470 | MT1B | 4490 | 2 | 7 | 34 | |
| GSE46452 | MT1B | 4490 | 38 | 1 | 20 | |
| GSE47630 | MT1B | 4490 | 10 | 8 | 22 | |
| GSE54993 | MT1B | 4490 | 2 | 4 | 64 | |
| GSE54994 | MT1B | 4490 | 7 | 10 | 36 | |
| GSE60625 | MT1B | 4490 | 4 | 0 | 7 | |
| GSE74703 | MT1B | 4490 | 2 | 4 | 30 | |
| GSE74704 | MT1B | 4490 | 4 | 0 | 16 | |
| TCGA | MT1B | 4490 | 25 | 13 | 58 |
Total number of gains: 104; Total number of losses: 48; Total Number of normals: 336.
Somatic mutations of MT1B:
Generating mutation plots.
Highly correlated genes for MT1B:
Showing all 5 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MT1B | MT1E | 0.854346 | 3 | 0 | 3 |
| MT1B | MT2A | 0.77364 | 3 | 0 | 3 |
| MT1B | MT1X | 0.745189 | 3 | 0 | 3 |
| MT1B | MT1M | 0.74088 | 3 | 0 | 3 |
| MT1B | MT1H | 0.664267 | 3 | 0 | 3 |
For details and further investigation, click here
