| Full name: metallothionein 1X | Alias Symbol: MT-1l | ||
| Type: protein-coding gene | Cytoband: 16q13 | ||
| Entrez ID: 4501 | HGNC ID: HGNC:7405 | Ensembl Gene: ENSG00000187193 | OMIM ID: 156359 |
| Drug and gene relationship at DGIdb | |||
Expression of MT1X:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MT1X | 4501 | 208581_x_at | -0.0760 | 0.9513 | |
| GSE20347 | MT1X | 4501 | 208581_x_at | 0.0935 | 0.7288 | |
| GSE23400 | MT1X | 4501 | 208581_x_at | -0.2238 | 0.1039 | |
| GSE26886 | MT1X | 4501 | 208581_x_at | -0.1555 | 0.8293 | |
| GSE29001 | MT1X | 4501 | 208581_x_at | -0.4046 | 0.2712 | |
| GSE38129 | MT1X | 4501 | 208581_x_at | 0.0806 | 0.7923 | |
| GSE45670 | MT1X | 4501 | 208581_x_at | -0.6155 | 0.0400 | |
| GSE53622 | MT1X | 4501 | 83653 | -0.8933 | 0.0000 | |
| GSE53624 | MT1X | 4501 | 83653 | -0.4442 | 0.0000 | |
| GSE63941 | MT1X | 4501 | 208581_x_at | -1.8377 | 0.1850 | |
| GSE77861 | MT1X | 4501 | 208581_x_at | -0.7036 | 0.1968 | |
| GSE97050 | MT1X | 4501 | A_33_P3350056 | -0.5617 | 0.2750 | |
| SRP007169 | MT1X | 4501 | RNAseq | -1.2029 | 0.0939 | |
| SRP008496 | MT1X | 4501 | RNAseq | -1.3075 | 0.0327 | |
| SRP064894 | MT1X | 4501 | RNAseq | -0.2751 | 0.5134 | |
| SRP133303 | MT1X | 4501 | RNAseq | -0.5605 | 0.1022 | |
| SRP159526 | MT1X | 4501 | RNAseq | -0.9666 | 0.0515 | |
| SRP193095 | MT1X | 4501 | RNAseq | -1.3623 | 0.0000 | |
| SRP219564 | MT1X | 4501 | RNAseq | -0.0861 | 0.8585 | |
| TCGA | MT1X | 4501 | RNAseq | -0.3284 | 0.0044 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by MT1X expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MT1X:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MT1X | 4501 | 5 | 0 | 25 | |
| GSE20123 | MT1X | 4501 | 5 | 1 | 24 | |
| GSE43470 | MT1X | 4501 | 2 | 7 | 34 | |
| GSE46452 | MT1X | 4501 | 38 | 1 | 20 | |
| GSE47630 | MT1X | 4501 | 10 | 8 | 22 | |
| GSE54993 | MT1X | 4501 | 2 | 4 | 64 | |
| GSE54994 | MT1X | 4501 | 7 | 10 | 36 | |
| GSE60625 | MT1X | 4501 | 4 | 0 | 7 | |
| GSE74703 | MT1X | 4501 | 2 | 4 | 30 | |
| GSE74704 | MT1X | 4501 | 4 | 0 | 16 | |
| TCGA | MT1X | 4501 | 25 | 13 | 58 |
Total number of gains: 104; Total number of losses: 48; Total Number of normals: 336.
Somatic mutations of MT1X:
Generating mutation plots.
Highly correlated genes for MT1X:
Showing top 20/137 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MT1X | MT1HL1 | 0.8757 | 11 | 0 | 10 |
| MT1X | MT1H | 0.862067 | 13 | 0 | 12 |
| MT1X | MT1F | 0.856898 | 11 | 0 | 10 |
| MT1X | MT2A | 0.815936 | 13 | 0 | 11 |
| MT1X | MT1G | 0.805959 | 11 | 0 | 9 |
| MT1X | MT1B | 0.745189 | 3 | 0 | 3 |
| MT1X | LEPROT | 0.732745 | 4 | 0 | 4 |
| MT1X | CHMP1B | 0.702451 | 3 | 0 | 3 |
| MT1X | MT1A | 0.700488 | 4 | 0 | 4 |
| MT1X | MT1E | 0.678666 | 13 | 0 | 11 |
| MT1X | KIFC3 | 0.676492 | 3 | 0 | 3 |
| MT1X | MBD5 | 0.658825 | 3 | 0 | 3 |
| MT1X | CD59 | 0.657938 | 4 | 0 | 4 |
| MT1X | CALY | 0.65477 | 4 | 0 | 4 |
| MT1X | STX4 | 0.647222 | 3 | 0 | 3 |
| MT1X | VDAC2 | 0.626419 | 4 | 0 | 3 |
| MT1X | PPP2CA | 0.624153 | 3 | 0 | 3 |
| MT1X | AGL | 0.617963 | 3 | 0 | 3 |
| MT1X | SNCA | 0.615185 | 5 | 0 | 3 |
| MT1X | FAS | 0.613585 | 3 | 0 | 3 |
For details and further investigation, click here
