NDUFS5

 

Full name: NADH:ubiquinone oxidoreductase subunit S5 Alias Symbol: CI-15k
Type: protein-coding gene Cytoband: 1p34.3
Entrez ID: 4725 HGNC ID: HGNC:7712 Ensembl Gene: ENSG00000168653 OMIM ID: 603847
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of NDUFS5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 NDUFS5 4725 109280 -0.1825 0.0009
GSE53624 NDUFS5 4725 109280 0.3149 0.0000
GSE97050 NDUFS5 4725 A_23_P10463 -0.2133 0.3997
SRP007169 NDUFS5 4725 RNAseq -0.5994 0.2110
SRP008496 NDUFS5 4725 RNAseq -0.7826 0.0026
SRP064894 NDUFS5 4725 RNAseq 0.2958 0.3883
SRP133303 NDUFS5 4725 RNAseq 0.1202 0.4860
SRP159526 NDUFS5 4725 RNAseq 0.5332 0.2467
SRP193095 NDUFS5 4725 RNAseq -0.4805 0.0071
SRP219564 NDUFS5 4725 RNAseq -0.1769 0.6145
TCGA NDUFS5 4725 RNAseq 0.0543 0.3826

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by NDUFS5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NDUFS5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NDUFS5 4725 3 4 23
GSE20123 NDUFS5 4725 2 3 25
GSE43470 NDUFS5 4725 7 2 34
GSE46452 NDUFS5 4725 4 1 54
GSE47630 NDUFS5 4725 8 4 28
GSE54993 NDUFS5 4725 0 1 69
GSE54994 NDUFS5 4725 13 2 38
GSE60625 NDUFS5 4725 0 0 11
GSE74703 NDUFS5 4725 6 1 29
GSE74704 NDUFS5 4725 1 0 19
TCGA NDUFS5 4725 15 16 65

Total number of gains: 59; Total number of losses: 34; Total Number of normals: 395.  

 

Somatic mutations of NDUFS5:

 

Generating mutation plots.

 

Highly correlated genes for NDUFS5:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NDUFS5SNRPF0.676835303
NDUFS5IMMP2L0.664489303
NDUFS5SRP140.661311303
NDUFS5EBNA1BP20.642195303
NDUFS5OTUD6B0.638138303
NDUFS5COX7C0.582521303

For details and further investigation, click here