| Full name: inner mitochondrial membrane peptidase subunit 2 | Alias Symbol: IMP2 | ||
| Type: protein-coding gene | Cytoband: 7q31.1 | ||
| Entrez ID: 83943 | HGNC ID: HGNC:14598 | Ensembl Gene: ENSG00000184903 | OMIM ID: 605977 |
| Drug and gene relationship at DGIdb | |||
Expression of IMMP2L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IMMP2L | 83943 | 227153_at | -0.3962 | 0.4013 | |
| GSE26886 | IMMP2L | 83943 | 227153_at | 0.3343 | 0.1980 | |
| GSE45670 | IMMP2L | 83943 | 227153_at | -0.4736 | 0.0210 | |
| GSE53622 | IMMP2L | 83943 | 25195 | -0.3341 | 0.0018 | |
| GSE53624 | IMMP2L | 83943 | 25195 | -0.1390 | 0.2269 | |
| GSE63941 | IMMP2L | 83943 | 227153_at | 0.1679 | 0.7848 | |
| GSE77861 | IMMP2L | 83943 | 227153_at | -0.1717 | 0.2557 | |
| GSE97050 | IMMP2L | 83943 | A_33_P3213377 | -0.1854 | 0.6412 | |
| SRP007169 | IMMP2L | 83943 | RNAseq | -1.1454 | 0.0343 | |
| SRP008496 | IMMP2L | 83943 | RNAseq | -0.0398 | 0.9203 | |
| SRP064894 | IMMP2L | 83943 | RNAseq | -0.0444 | 0.8282 | |
| SRP133303 | IMMP2L | 83943 | RNAseq | -0.1322 | 0.4368 | |
| SRP159526 | IMMP2L | 83943 | RNAseq | -1.1809 | 0.0000 | |
| SRP193095 | IMMP2L | 83943 | RNAseq | -0.1531 | 0.3485 | |
| SRP219564 | IMMP2L | 83943 | RNAseq | -0.3134 | 0.5747 | |
| TCGA | IMMP2L | 83943 | RNAseq | -0.3351 | 0.0127 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by IMMP2L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IMMP2L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IMMP2L | 83943 | 11 | 2 | 17 | |
| GSE20123 | IMMP2L | 83943 | 11 | 2 | 17 | |
| GSE43470 | IMMP2L | 83943 | 7 | 2 | 34 | |
| GSE46452 | IMMP2L | 83943 | 8 | 1 | 50 | |
| GSE47630 | IMMP2L | 83943 | 7 | 5 | 28 | |
| GSE54993 | IMMP2L | 83943 | 3 | 8 | 59 | |
| GSE54994 | IMMP2L | 83943 | 13 | 5 | 35 | |
| GSE60625 | IMMP2L | 83943 | 0 | 0 | 11 | |
| GSE74703 | IMMP2L | 83943 | 7 | 2 | 27 | |
| GSE74704 | IMMP2L | 83943 | 7 | 2 | 11 | |
| TCGA | IMMP2L | 83943 | 39 | 20 | 37 |
Total number of gains: 113; Total number of losses: 49; Total Number of normals: 326.
Somatic mutations of IMMP2L:
Generating mutation plots.
Highly correlated genes for IMMP2L:
Showing top 20/221 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IMMP2L | FNIP2 | 0.779776 | 3 | 0 | 3 |
| IMMP2L | CRBN | 0.744642 | 3 | 0 | 3 |
| IMMP2L | CKB | 0.728529 | 3 | 0 | 3 |
| IMMP2L | INMT | 0.713499 | 3 | 0 | 3 |
| IMMP2L | TMEM50B | 0.713357 | 3 | 0 | 3 |
| IMMP2L | AXL | 0.703729 | 3 | 0 | 3 |
| IMMP2L | ZMYND11 | 0.698972 | 4 | 0 | 3 |
| IMMP2L | WDR35 | 0.694647 | 4 | 0 | 4 |
| IMMP2L | KLHL9 | 0.684579 | 3 | 0 | 3 |
| IMMP2L | PPP2CB | 0.676164 | 4 | 0 | 3 |
| IMMP2L | HSF2 | 0.673061 | 3 | 0 | 3 |
| IMMP2L | FAM13B | 0.671465 | 5 | 0 | 3 |
| IMMP2L | DIS3L | 0.671178 | 3 | 0 | 3 |
| IMMP2L | PRKAB2 | 0.668554 | 3 | 0 | 3 |
| IMMP2L | TADA2B | 0.668224 | 3 | 0 | 3 |
| IMMP2L | CBY1 | 0.667435 | 4 | 0 | 3 |
| IMMP2L | NDUFS5 | 0.664489 | 3 | 0 | 3 |
| IMMP2L | HMGN5 | 0.660288 | 3 | 0 | 3 |
| IMMP2L | DCP1A | 0.659948 | 3 | 0 | 3 |
| IMMP2L | RBM7 | 0.659716 | 3 | 0 | 3 |
For details and further investigation, click here
