NXPH1

 

Full name: neurexophilin 1 Alias Symbol: 
Type: protein-coding gene Cytoband: 7p21.3
Entrez ID: 30010 HGNC ID: HGNC:20693 Ensembl Gene: ENSG00000122584 OMIM ID: 604639
Drug and gene relationship at DGIdb

 

Expression of NXPH1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NXPH1 30010 232377_at -0.0057 0.9827
GSE26886 NXPH1 30010 232377_at 0.1147 0.1210
GSE45670 NXPH1 30010 232377_at 0.0460 0.4127
GSE63941 NXPH1 30010 232377_at 0.1661 0.5850
GSE77861 NXPH1 30010 232377_at -0.0996 0.1651
TCGA NXPH1 30010 RNAseq 3.5455 0.0017

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by NXPH1 expression:

 

TCGA

 

Note: Click image to view full size file.  

Copy number change of NXPH1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NXPH1 30010 15 2 13
GSE20123 NXPH1 30010 15 2 13
GSE43470 NXPH1 30010 8 0 35
GSE46452 NXPH1 30010 11 1 47
GSE47630 NXPH1 30010 9 1 30
GSE54993 NXPH1 30010 0 6 64
GSE54994 NXPH1 30010 22 1 30
GSE60625 NXPH1 30010 0 0 11
GSE74703 NXPH1 30010 8 0 28
GSE74704 NXPH1 30010 9 2 9
TCGA NXPH1 30010 56 5 35

Total number of gains: 153; Total number of losses: 20; Total Number of normals: 315.  

 

Somatic mutations of NXPH1:

 

Generating mutation plots.

 

Highly correlated genes for NXPH1:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NXPH1RAB420.700008303
NXPH1ZNF7100.689287303
NXPH1B3GNT60.568502303
NXPH1EFHB0.564711303
NXPH1SLC18A10.561682303
NXPH1SPPL2B0.513456403

For details and further investigation, click here