| Full name: UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 | Alias Symbol: B3Gn-T6 | ||
| Type: protein-coding gene | Cytoband: 11q13.5 | ||
| Entrez ID: 192134 | HGNC ID: HGNC:24141 | Ensembl Gene: ENSG00000198488 | OMIM ID: 615315 |
| Drug and gene relationship at DGIdb | |||
Expression of B3GNT6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | B3GNT6 | 192134 | 1552834_at | -0.5137 | 0.3191 | |
| GSE26886 | B3GNT6 | 192134 | 1552834_at | -0.6528 | 0.0013 | |
| GSE45670 | B3GNT6 | 192134 | 1552834_at | 0.0083 | 0.9803 | |
| GSE53622 | B3GNT6 | 192134 | 33375 | -3.1323 | 0.0000 | |
| GSE53624 | B3GNT6 | 192134 | 33375 | -2.5873 | 0.0000 | |
| GSE63941 | B3GNT6 | 192134 | 1552833_at | 0.4497 | 0.0970 | |
| GSE77861 | B3GNT6 | 192134 | 1552834_at | -0.2921 | 0.0965 | |
| SRP007169 | B3GNT6 | 192134 | RNAseq | -2.6719 | 0.0018 | |
| SRP064894 | B3GNT6 | 192134 | RNAseq | -3.8927 | 0.0000 | |
| SRP133303 | B3GNT6 | 192134 | RNAseq | -2.0838 | 0.0308 | |
| SRP159526 | B3GNT6 | 192134 | RNAseq | -5.4285 | 0.0000 | |
| SRP193095 | B3GNT6 | 192134 | RNAseq | -2.5112 | 0.0000 | |
| TCGA | B3GNT6 | 192134 | RNAseq | -2.4460 | 0.0077 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by B3GNT6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of B3GNT6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | B3GNT6 | 192134 | 5 | 9 | 16 | |
| GSE20123 | B3GNT6 | 192134 | 5 | 8 | 17 | |
| GSE43470 | B3GNT6 | 192134 | 3 | 3 | 37 | |
| GSE46452 | B3GNT6 | 192134 | 7 | 22 | 30 | |
| GSE47630 | B3GNT6 | 192134 | 5 | 16 | 19 | |
| GSE54993 | B3GNT6 | 192134 | 8 | 2 | 60 | |
| GSE54994 | B3GNT6 | 192134 | 7 | 17 | 29 | |
| GSE60625 | B3GNT6 | 192134 | 4 | 3 | 4 | |
| GSE74703 | B3GNT6 | 192134 | 2 | 2 | 32 | |
| GSE74704 | B3GNT6 | 192134 | 3 | 4 | 13 | |
| TCGA | B3GNT6 | 192134 | 20 | 31 | 45 |
Total number of gains: 69; Total number of losses: 117; Total Number of normals: 302.
Somatic mutations of B3GNT6:
Generating mutation plots.
Highly correlated genes for B3GNT6:
Showing top 20/958 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| B3GNT6 | SLC13A4 | 0.775401 | 6 | 0 | 6 |
| B3GNT6 | IQCF1 | 0.764933 | 3 | 0 | 3 |
| B3GNT6 | MUC1 | 0.762981 | 6 | 0 | 6 |
| B3GNT6 | CAPN5 | 0.758952 | 6 | 0 | 6 |
| B3GNT6 | BOK | 0.757696 | 4 | 0 | 4 |
| B3GNT6 | SCNN1B | 0.748972 | 6 | 0 | 6 |
| B3GNT6 | RASAL1 | 0.747453 | 6 | 0 | 6 |
| B3GNT6 | CEACAM5 | 0.745714 | 6 | 0 | 6 |
| B3GNT6 | PRSS27 | 0.745226 | 6 | 0 | 6 |
| B3GNT6 | MORN3 | 0.74445 | 3 | 0 | 3 |
| B3GNT6 | CCNYL1 | 0.742425 | 3 | 0 | 3 |
| B3GNT6 | CEACAM7 | 0.740487 | 6 | 0 | 6 |
| B3GNT6 | ECM1 | 0.73795 | 6 | 0 | 6 |
| B3GNT6 | BTBD19 | 0.736799 | 3 | 0 | 3 |
| B3GNT6 | PHACTR4 | 0.736584 | 6 | 0 | 6 |
| B3GNT6 | SMIM5 | 0.734489 | 6 | 0 | 6 |
| B3GNT6 | SMAGP | 0.729554 | 6 | 0 | 6 |
| B3GNT6 | DEGS2 | 0.729291 | 6 | 0 | 6 |
| B3GNT6 | C15orf48 | 0.726989 | 6 | 0 | 6 |
| B3GNT6 | CEACAM1 | 0.725416 | 6 | 0 | 6 |
For details and further investigation, click here
