EFHB

 

Full name: EF-hand domain family member B Alias Symbol: FLJ25200|CFAP21
Type: protein-coding gene Cytoband: 3p24.3
Entrez ID: 151651 HGNC ID: HGNC:26330 Ensembl Gene: ENSG00000163576 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of EFHB:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 EFHB 151651 1557840_at -0.0376 0.8543
GSE26886 EFHB 151651 1557840_at -0.0105 0.9401
GSE45670 EFHB 151651 1557840_at -0.0365 0.6654
GSE53622 EFHB 151651 55772 -0.2970 0.0455
GSE53624 EFHB 151651 55772 -0.1194 0.4845
GSE63941 EFHB 151651 1557840_at 0.1012 0.4456
GSE77861 EFHB 151651 1557840_at -0.1140 0.3534
SRP133303 EFHB 151651 RNAseq -0.0940 0.7843
TCGA EFHB 151651 RNAseq -0.4746 0.5083

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by EFHB expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of EFHB:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 EFHB 151651 0 19 11
GSE20123 EFHB 151651 0 19 11
GSE43470 EFHB 151651 0 20 23
GSE46452 EFHB 151651 2 17 40
GSE47630 EFHB 151651 1 24 15
GSE54993 EFHB 151651 6 1 63
GSE54994 EFHB 151651 1 32 20
GSE60625 EFHB 151651 5 0 6
GSE74703 EFHB 151651 0 17 19
GSE74704 EFHB 151651 0 13 7
TCGA EFHB 151651 0 69 27

Total number of gains: 15; Total number of losses: 231; Total Number of normals: 242.  

 

Somatic mutations of EFHB:

 

Generating mutation plots.

 

Highly correlated genes for EFHB:

 

Showing all 9 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
EFHBCYP2D60.700831303
EFHBTTLL120.689418303
EFHBPLCB30.591647303
EFHBMAGEB180.573415303
EFHBDUSP130.567752303
EFHBNXPH10.564711303
EFHBANKRD240.561726303
EFHBTSPAN160.55578303
EFHBGPR150.543684303

For details and further investigation, click here