OR4E2

 

Full name: olfactory receptor family 4 subfamily E member 2 Alias Symbol: 
Type: protein-coding gene Cytoband: 14q11.2
Entrez ID: 26686 HGNC ID: HGNC:8297 Ensembl Gene: ENSG00000221977 OMIM ID: 
Drug and gene relationship at DGIdb

 

OR4E2 involved pathways:

KEGG pathway Description View
hsa04740Olfactory transduction

 

Expression of OR4E2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 OR4E2 26686 21922 0.2020 0.0010
GSE53624 OR4E2 26686 21922 0.3236 0.0000
GSE97050 OR4E2 26686 A_33_P3272385 0.1396 0.4953

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by OR4E2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of OR4E2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 OR4E2 26686 9 2 19
GSE20123 OR4E2 26686 9 2 19
GSE43470 OR4E2 26686 7 1 35
GSE46452 OR4E2 26686 18 2 39
GSE47630 OR4E2 26686 10 10 20
GSE54993 OR4E2 26686 3 11 56
GSE54994 OR4E2 26686 17 6 30
GSE60625 OR4E2 26686 0 2 9
GSE74703 OR4E2 26686 6 1 29
GSE74704 OR4E2 26686 4 1 15
TCGA OR4E2 26686 25 17 54

Total number of gains: 108; Total number of losses: 55; Total Number of normals: 325.  

 

Somatic mutations of OR4E2:

 

Generating mutation plots.

 

Highly correlated genes for OR4E2:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
OR4E2SYCE30.741097303
OR4E2SIGLEC70.727631303
OR4E2SIRPD0.716853303
OR4E2TRAIP0.714542303
OR4E2OR2Y10.709942303
OR4E2DFFB0.701639303

For details and further investigation, click here