| Full name: synaptonemal complex central element protein 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 22q13.33 | ||
| Entrez ID: 644186 | HGNC ID: HGNC:35245 | Ensembl Gene: ENSG00000217442 | OMIM ID: 615775 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of SYCE3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SYCE3 | 644186 | 239854_at | -0.1208 | 0.5790 | |
| GSE26886 | SYCE3 | 644186 | 239854_at | 0.6660 | 0.0001 | |
| GSE45670 | SYCE3 | 644186 | 239854_at | 0.1906 | 0.0525 | |
| GSE53622 | SYCE3 | 644186 | 18060 | 0.2243 | 0.0028 | |
| GSE53624 | SYCE3 | 644186 | 18060 | 0.6830 | 0.0000 | |
| GSE63941 | SYCE3 | 644186 | 239854_at | 0.7369 | 0.0996 | |
| GSE77861 | SYCE3 | 644186 | 239854_at | -0.0513 | 0.7854 | |
| GSE97050 | SYCE3 | 644186 | A_33_P3250887 | 0.1136 | 0.5584 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SYCE3 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SYCE3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SYCE3 | 644186 | 3 | 8 | 19 | |
| GSE20123 | SYCE3 | 644186 | 3 | 8 | 19 | |
| GSE43470 | SYCE3 | 644186 | 2 | 8 | 33 | |
| GSE46452 | SYCE3 | 644186 | 31 | 2 | 26 | |
| GSE47630 | SYCE3 | 644186 | 9 | 4 | 27 | |
| GSE54993 | SYCE3 | 644186 | 4 | 6 | 60 | |
| GSE54994 | SYCE3 | 644186 | 11 | 8 | 34 | |
| GSE60625 | SYCE3 | 644186 | 5 | 0 | 6 | |
| GSE74703 | SYCE3 | 644186 | 2 | 6 | 28 | |
| GSE74704 | SYCE3 | 644186 | 1 | 4 | 15 | |
| TCGA | SYCE3 | 644186 | 26 | 16 | 54 |
Total number of gains: 97; Total number of losses: 70; Total Number of normals: 321.
Somatic mutations of SYCE3:
Generating mutation plots.
Highly correlated genes for SYCE3:
Showing top 20/167 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SYCE3 | DOK7 | 0.792916 | 3 | 0 | 3 |
| SYCE3 | DIO3 | 0.7902 | 3 | 0 | 3 |
| SYCE3 | ZSWIM3 | 0.756291 | 3 | 0 | 3 |
| SYCE3 | KCNJ13 | 0.742665 | 4 | 0 | 4 |
| SYCE3 | OR4E2 | 0.741097 | 3 | 0 | 3 |
| SYCE3 | NOXA1 | 0.736657 | 3 | 0 | 3 |
| SYCE3 | SP7 | 0.733309 | 3 | 0 | 3 |
| SYCE3 | OTOP2 | 0.732278 | 4 | 0 | 3 |
| SYCE3 | CHD5 | 0.731897 | 3 | 0 | 3 |
| SYCE3 | C3orf36 | 0.731116 | 3 | 0 | 3 |
| SYCE3 | GFRA2 | 0.729522 | 3 | 0 | 3 |
| SYCE3 | IGFL2 | 0.728162 | 3 | 0 | 3 |
| SYCE3 | SLC22A8 | 0.723733 | 3 | 0 | 3 |
| SYCE3 | RALYL | 0.723558 | 3 | 0 | 3 |
| SYCE3 | FGF18 | 0.722823 | 3 | 0 | 3 |
| SYCE3 | ADRA2C | 0.72128 | 4 | 0 | 3 |
| SYCE3 | NPPA | 0.71988 | 3 | 0 | 3 |
| SYCE3 | LTC4S | 0.712265 | 3 | 0 | 3 |
| SYCE3 | OR2H2 | 0.710502 | 3 | 0 | 3 |
| SYCE3 | OR10W1 | 0.709108 | 3 | 0 | 3 |
For details and further investigation, click here
