| Full name: TRAF interacting protein | Alias Symbol: TRIP|RNF206 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 10293 | HGNC ID: HGNC:30764 | Ensembl Gene: ENSG00000183763 | OMIM ID: 605958 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of TRAIP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TRAIP | 10293 | 205598_at | 0.5649 | 0.1213 | |
| GSE20347 | TRAIP | 10293 | 205598_at | 0.3986 | 0.0000 | |
| GSE23400 | TRAIP | 10293 | 205598_at | 0.1281 | 0.0021 | |
| GSE26886 | TRAIP | 10293 | 205598_at | 0.1001 | 0.3904 | |
| GSE29001 | TRAIP | 10293 | 205598_at | 0.2472 | 0.1115 | |
| GSE38129 | TRAIP | 10293 | 205598_at | 0.3913 | 0.0001 | |
| GSE45670 | TRAIP | 10293 | 205598_at | 0.4002 | 0.0041 | |
| GSE53622 | TRAIP | 10293 | 73794 | 0.2316 | 0.0000 | |
| GSE53624 | TRAIP | 10293 | 73794 | 0.6480 | 0.0000 | |
| GSE63941 | TRAIP | 10293 | 205598_at | 1.0432 | 0.0004 | |
| GSE77861 | TRAIP | 10293 | 205598_at | -0.0283 | 0.8099 | |
| GSE97050 | TRAIP | 10293 | A_23_P170491 | 0.2980 | 0.3451 | |
| SRP007169 | TRAIP | 10293 | RNAseq | 0.9555 | 0.1411 | |
| SRP064894 | TRAIP | 10293 | RNAseq | 1.1162 | 0.0001 | |
| SRP133303 | TRAIP | 10293 | RNAseq | 0.8778 | 0.0007 | |
| SRP159526 | TRAIP | 10293 | RNAseq | 1.3266 | 0.0007 | |
| SRP193095 | TRAIP | 10293 | RNAseq | 0.7691 | 0.0000 | |
| SRP219564 | TRAIP | 10293 | RNAseq | 0.7580 | 0.1604 | |
| TCGA | TRAIP | 10293 | RNAseq | 1.0039 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by TRAIP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TRAIP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TRAIP | 10293 | 0 | 18 | 12 | |
| GSE20123 | TRAIP | 10293 | 0 | 19 | 11 | |
| GSE43470 | TRAIP | 10293 | 0 | 17 | 26 | |
| GSE46452 | TRAIP | 10293 | 2 | 16 | 41 | |
| GSE47630 | TRAIP | 10293 | 1 | 24 | 15 | |
| GSE54993 | TRAIP | 10293 | 6 | 2 | 62 | |
| GSE54994 | TRAIP | 10293 | 0 | 35 | 18 | |
| GSE60625 | TRAIP | 10293 | 5 | 0 | 6 | |
| GSE74703 | TRAIP | 10293 | 0 | 14 | 22 | |
| GSE74704 | TRAIP | 10293 | 0 | 12 | 8 | |
| TCGA | TRAIP | 10293 | 0 | 77 | 19 |
Total number of gains: 14; Total number of losses: 234; Total Number of normals: 240.
Somatic mutations of TRAIP:
Generating mutation plots.
Highly correlated genes for TRAIP:
Showing top 20/262 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TRAIP | NRIP3 | 0.800555 | 3 | 0 | 3 |
| TRAIP | ARHGAP21 | 0.741299 | 3 | 0 | 3 |
| TRAIP | OR4E2 | 0.714542 | 3 | 0 | 3 |
| TRAIP | WDR90 | 0.713624 | 4 | 0 | 4 |
| TRAIP | KLK3 | 0.712546 | 3 | 0 | 3 |
| TRAIP | BAX | 0.712517 | 4 | 0 | 4 |
| TRAIP | DAO | 0.701742 | 3 | 0 | 3 |
| TRAIP | ZNF519 | 0.701043 | 3 | 0 | 3 |
| TRAIP | PGAM5 | 0.691352 | 5 | 0 | 5 |
| TRAIP | TNFAIP8L1 | 0.687886 | 5 | 0 | 4 |
| TRAIP | SEC62 | 0.686767 | 3 | 0 | 3 |
| TRAIP | RFX8 | 0.686033 | 3 | 0 | 3 |
| TRAIP | SULT1C3 | 0.685845 | 3 | 0 | 3 |
| TRAIP | BEND3 | 0.683448 | 6 | 0 | 6 |
| TRAIP | LRR1 | 0.681622 | 6 | 0 | 5 |
| TRAIP | LRWD1 | 0.680949 | 3 | 0 | 3 |
| TRAIP | SPATA2L | 0.678785 | 4 | 0 | 3 |
| TRAIP | DOHH | 0.668812 | 3 | 0 | 3 |
| TRAIP | POLQ | 0.66788 | 10 | 0 | 7 |
| TRAIP | UBE2S | 0.65878 | 6 | 0 | 4 |
For details and further investigation, click here
