| Full name: signal regulatory protein delta | Alias Symbol: dJ576H24.4 | ||
| Type: protein-coding gene | Cytoband: 20p13 | ||
| Entrez ID: 128646 | HGNC ID: HGNC:16248 | Ensembl Gene: ENSG00000125900 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of SIRPD:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SIRPD | 128646 | 232891_at | -0.0524 | 0.8019 | |
| GSE26886 | SIRPD | 128646 | 232891_at | -0.0596 | 0.6222 | |
| GSE45670 | SIRPD | 128646 | 232891_at | -0.0460 | 0.4972 | |
| GSE53622 | SIRPD | 128646 | 90673 | 0.2103 | 0.0009 | |
| GSE53624 | SIRPD | 128646 | 90673 | 0.3009 | 0.0000 | |
| GSE63941 | SIRPD | 128646 | 232891_at | -0.0189 | 0.8851 | |
| GSE77861 | SIRPD | 128646 | 232891_at | -0.1140 | 0.3319 | |
| GSE97050 | SIRPD | 128646 | A_33_P3244610 | 0.0395 | 0.8544 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SIRPD expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SIRPD:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SIRPD | 128646 | 13 | 3 | 14 | |
| GSE20123 | SIRPD | 128646 | 14 | 3 | 13 | |
| GSE43470 | SIRPD | 128646 | 11 | 1 | 31 | |
| GSE46452 | SIRPD | 128646 | 26 | 1 | 32 | |
| GSE47630 | SIRPD | 128646 | 19 | 4 | 17 | |
| GSE54993 | SIRPD | 128646 | 2 | 14 | 54 | |
| GSE54994 | SIRPD | 128646 | 24 | 2 | 27 | |
| GSE60625 | SIRPD | 128646 | 0 | 0 | 11 | |
| GSE74703 | SIRPD | 128646 | 10 | 1 | 25 | |
| GSE74704 | SIRPD | 128646 | 9 | 1 | 10 | |
| TCGA | SIRPD | 128646 | 40 | 11 | 45 |
Total number of gains: 168; Total number of losses: 41; Total Number of normals: 279.
Somatic mutations of SIRPD:
Generating mutation plots.
Highly correlated genes for SIRPD:
Showing top 20/73 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SIRPD | MCF2L | 0.861601 | 3 | 0 | 3 |
| SIRPD | BTK | 0.748882 | 3 | 0 | 3 |
| SIRPD | MFNG | 0.740275 | 3 | 0 | 3 |
| SIRPD | PPP1R27 | 0.731811 | 3 | 0 | 3 |
| SIRPD | PAX2 | 0.728985 | 3 | 0 | 3 |
| SIRPD | OR4E2 | 0.716853 | 3 | 0 | 3 |
| SIRPD | ADRA2A | 0.713405 | 4 | 0 | 3 |
| SIRPD | GABRD | 0.709079 | 3 | 0 | 3 |
| SIRPD | TEX22 | 0.703914 | 4 | 0 | 3 |
| SIRPD | ZCCHC18 | 0.700381 | 3 | 0 | 3 |
| SIRPD | ABCB1 | 0.700101 | 3 | 0 | 3 |
| SIRPD | COX4I2 | 0.699051 | 3 | 0 | 3 |
| SIRPD | SYT2 | 0.697716 | 3 | 0 | 3 |
| SIRPD | CYP46A1 | 0.693111 | 3 | 0 | 3 |
| SIRPD | SLC25A18 | 0.689563 | 3 | 0 | 3 |
| SIRPD | PAX7 | 0.689557 | 3 | 0 | 3 |
| SIRPD | MUC2 | 0.68943 | 3 | 0 | 3 |
| SIRPD | DPYSL4 | 0.688798 | 3 | 0 | 3 |
| SIRPD | EPHA10 | 0.674114 | 3 | 0 | 3 |
| SIRPD | LINC00567 | 0.669578 | 3 | 0 | 3 |
For details and further investigation, click here
