| Full name: DNA fragmentation factor subunit beta | Alias Symbol: CAD|CPAN|DFF-40|DFF40 | ||
| Type: protein-coding gene | Cytoband: 1p36.32 | ||
| Entrez ID: 1677 | HGNC ID: HGNC:2773 | Ensembl Gene: ENSG00000169598 | OMIM ID: 601883 |
| Drug and gene relationship at DGIdb | |||
Expression of DFFB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DFFB | 1677 | 206752_s_at | 0.6426 | 0.0559 | |
| GSE20347 | DFFB | 1677 | 206752_s_at | 0.3925 | 0.0202 | |
| GSE23400 | DFFB | 1677 | 206752_s_at | 0.1714 | 0.0001 | |
| GSE26886 | DFFB | 1677 | 206752_s_at | 1.1064 | 0.0052 | |
| GSE29001 | DFFB | 1677 | 206752_s_at | 0.4000 | 0.1412 | |
| GSE38129 | DFFB | 1677 | 206752_s_at | 0.4574 | 0.0113 | |
| GSE45670 | DFFB | 1677 | 206752_s_at | 0.3460 | 0.1849 | |
| GSE53622 | DFFB | 1677 | 72626 | 0.1531 | 0.0048 | |
| GSE53624 | DFFB | 1677 | 72626 | 0.2029 | 0.0004 | |
| GSE63941 | DFFB | 1677 | 206752_s_at | -0.7981 | 0.1618 | |
| GSE77861 | DFFB | 1677 | 206752_s_at | 0.0888 | 0.5209 | |
| GSE97050 | DFFB | 1677 | A_33_P3277012 | 0.0042 | 0.9892 | |
| SRP007169 | DFFB | 1677 | RNAseq | 0.7930 | 0.2926 | |
| SRP064894 | DFFB | 1677 | RNAseq | 0.4760 | 0.0045 | |
| SRP133303 | DFFB | 1677 | RNAseq | 0.0524 | 0.6028 | |
| SRP159526 | DFFB | 1677 | RNAseq | 0.6156 | 0.1016 | |
| SRP193095 | DFFB | 1677 | RNAseq | 0.1476 | 0.2577 | |
| SRP219564 | DFFB | 1677 | RNAseq | 0.5681 | 0.0962 | |
| TCGA | DFFB | 1677 | RNAseq | -0.1285 | 0.1648 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by DFFB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DFFB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DFFB | 1677 | 4 | 6 | 20 | |
| GSE20123 | DFFB | 1677 | 4 | 5 | 21 | |
| GSE43470 | DFFB | 1677 | 3 | 5 | 35 | |
| GSE46452 | DFFB | 1677 | 7 | 1 | 51 | |
| GSE47630 | DFFB | 1677 | 8 | 4 | 28 | |
| GSE54993 | DFFB | 1677 | 3 | 2 | 65 | |
| GSE54994 | DFFB | 1677 | 14 | 3 | 36 | |
| GSE60625 | DFFB | 1677 | 0 | 0 | 11 | |
| GSE74703 | DFFB | 1677 | 3 | 3 | 30 | |
| GSE74704 | DFFB | 1677 | 4 | 0 | 16 | |
| TCGA | DFFB | 1677 | 14 | 20 | 62 |
Total number of gains: 64; Total number of losses: 49; Total Number of normals: 375.
Somatic mutations of DFFB:
Generating mutation plots.
Highly correlated genes for DFFB:
Showing top 20/243 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DFFB | DPM3 | 0.767443 | 3 | 0 | 3 |
| DFFB | C2CD4D | 0.760491 | 3 | 0 | 3 |
| DFFB | C19orf71 | 0.750639 | 3 | 0 | 3 |
| DFFB | ASMTL | 0.746199 | 3 | 0 | 3 |
| DFFB | CHGB | 0.742139 | 3 | 0 | 3 |
| DFFB | INF2 | 0.734623 | 3 | 0 | 3 |
| DFFB | PLEC | 0.733919 | 4 | 0 | 4 |
| DFFB | NKX6-3 | 0.727547 | 3 | 0 | 3 |
| DFFB | TTLL9 | 0.724912 | 3 | 0 | 3 |
| DFFB | DCPS | 0.721623 | 3 | 0 | 3 |
| DFFB | SHISA7 | 0.716875 | 4 | 0 | 3 |
| DFFB | ZBTB46 | 0.71352 | 4 | 0 | 3 |
| DFFB | OR4E2 | 0.701639 | 3 | 0 | 3 |
| DFFB | DNAH10OS | 0.700023 | 3 | 0 | 3 |
| DFFB | ZBTB24 | 0.697147 | 5 | 0 | 4 |
| DFFB | TMEM9 | 0.695651 | 4 | 0 | 4 |
| DFFB | ZDHHC8 | 0.689327 | 4 | 0 | 3 |
| DFFB | ZNF329 | 0.675632 | 4 | 0 | 3 |
| DFFB | SCUBE1 | 0.673774 | 3 | 0 | 3 |
| DFFB | PRDM13 | 0.673395 | 6 | 0 | 5 |
For details and further investigation, click here
