PADI6

 

Full name: peptidyl arginine deiminase 6 Alias Symbol: 
Type: protein-coding gene Cytoband: 1p36.13
Entrez ID: 353238 HGNC ID: HGNC:20449 Ensembl Gene: ENSG00000276747 OMIM ID: 610363
Drug and gene relationship at DGIdb

 

Expression of PADI6:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 PADI6 353238 11110 -0.2105 0.0023
GSE53624 PADI6 353238 11110 -0.1099 0.1283
GSE97050 PADI6 353238 A_33_P3358213 -0.0442 0.8640

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PADI6 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PADI6:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PADI6 353238 0 5 25
GSE20123 PADI6 353238 0 4 26
GSE43470 PADI6 353238 0 8 35
GSE46452 PADI6 353238 5 1 53
GSE47630 PADI6 353238 8 3 29
GSE54993 PADI6 353238 3 1 66
GSE54994 PADI6 353238 10 4 39
GSE60625 PADI6 353238 0 0 11
GSE74703 PADI6 353238 0 5 31
GSE74704 PADI6 353238 0 0 20
TCGA PADI6 353238 10 22 64

Total number of gains: 36; Total number of losses: 53; Total Number of normals: 399.  

 

Somatic mutations of PADI6:

 

Generating mutation plots.

 

Highly correlated genes for PADI6:

 

Showing all 7 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PADI6CACNA1G0.773209303
PADI6SEC14L30.724593303
PADI6BPIFB40.706353303
PADI6CCDC1660.697718303
PADI6GRIN10.683564303
PADI6FBXO240.662385303
PADI6AOC20.658858303

For details and further investigation, click here