| Full name: amine oxidase copper containing 2 | Alias Symbol: RAO|DAO2 | ||
| Type: protein-coding gene | Cytoband: 17q21.31 | ||
| Entrez ID: 314 | HGNC ID: HGNC:549 | Ensembl Gene: ENSG00000131480 | OMIM ID: 602268 |
| Drug and gene relationship at DGIdb | |||
Expression of AOC2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | AOC2 | 314 | 207064_s_at | -0.0069 | 0.9870 | |
| GSE20347 | AOC2 | 314 | 207064_s_at | -0.1249 | 0.1916 | |
| GSE23400 | AOC2 | 314 | 207064_s_at | -0.1016 | 0.0233 | |
| GSE26886 | AOC2 | 314 | 207064_s_at | -0.0842 | 0.4721 | |
| GSE29001 | AOC2 | 314 | 207064_s_at | -0.0038 | 0.9869 | |
| GSE38129 | AOC2 | 314 | 207064_s_at | -0.1485 | 0.1036 | |
| GSE45670 | AOC2 | 314 | 207064_s_at | 0.4094 | 0.0051 | |
| GSE53622 | AOC2 | 314 | 44410 | 0.0766 | 0.3950 | |
| GSE53624 | AOC2 | 314 | 44410 | 0.0062 | 0.9426 | |
| GSE63941 | AOC2 | 314 | 207064_s_at | 1.0304 | 0.0590 | |
| GSE77861 | AOC2 | 314 | 207064_s_at | 0.0680 | 0.6180 | |
| GSE97050 | AOC2 | 314 | A_23_P4133 | 0.0676 | 0.8152 | |
| SRP133303 | AOC2 | 314 | RNAseq | 0.3979 | 0.1291 | |
| SRP159526 | AOC2 | 314 | RNAseq | 0.6538 | 0.2370 | |
| SRP219564 | AOC2 | 314 | RNAseq | 0.7006 | 0.1592 | |
| TCGA | AOC2 | 314 | RNAseq | 0.2914 | 0.1923 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by AOC2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of AOC2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | AOC2 | 314 | 6 | 2 | 22 | |
| GSE20123 | AOC2 | 314 | 6 | 2 | 22 | |
| GSE43470 | AOC2 | 314 | 1 | 2 | 40 | |
| GSE46452 | AOC2 | 314 | 34 | 0 | 25 | |
| GSE47630 | AOC2 | 314 | 8 | 1 | 31 | |
| GSE54993 | AOC2 | 314 | 3 | 4 | 63 | |
| GSE54994 | AOC2 | 314 | 8 | 5 | 40 | |
| GSE60625 | AOC2 | 314 | 4 | 0 | 7 | |
| GSE74703 | AOC2 | 314 | 1 | 1 | 34 | |
| GSE74704 | AOC2 | 314 | 4 | 1 | 15 | |
| TCGA | AOC2 | 314 | 22 | 7 | 67 |
Total number of gains: 97; Total number of losses: 25; Total Number of normals: 366.
Somatic mutations of AOC2:
Generating mutation plots.
Highly correlated genes for AOC2:
Showing top 20/491 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| AOC2 | MAG | 0.791933 | 3 | 0 | 3 |
| AOC2 | OR2Y1 | 0.782792 | 3 | 0 | 3 |
| AOC2 | ISLR2 | 0.771806 | 3 | 0 | 3 |
| AOC2 | TTBK1 | 0.742855 | 3 | 0 | 3 |
| AOC2 | DNAI1 | 0.74212 | 4 | 0 | 4 |
| AOC2 | ESPNL | 0.737937 | 3 | 0 | 3 |
| AOC2 | PIP5KL1 | 0.723763 | 3 | 0 | 3 |
| AOC2 | EPHA10 | 0.720562 | 3 | 0 | 3 |
| AOC2 | TM6SF2 | 0.720054 | 3 | 0 | 3 |
| AOC2 | POU4F3 | 0.715415 | 3 | 0 | 3 |
| AOC2 | FAM189A1 | 0.710357 | 4 | 0 | 4 |
| AOC2 | PRODH2 | 0.704942 | 6 | 0 | 5 |
| AOC2 | TCP10L | 0.699967 | 4 | 0 | 4 |
| AOC2 | CYP17A1 | 0.69652 | 4 | 0 | 3 |
| AOC2 | TERT | 0.692992 | 5 | 0 | 4 |
| AOC2 | FASLG | 0.692894 | 5 | 0 | 4 |
| AOC2 | ELSPBP1 | 0.690956 | 3 | 0 | 3 |
| AOC2 | MATN1 | 0.68994 | 4 | 0 | 3 |
| AOC2 | TMPRSS5 | 0.68964 | 5 | 0 | 5 |
| AOC2 | IL9R | 0.689478 | 5 | 0 | 4 |
For details and further investigation, click here
