FBXO24

 

Full name: F-box protein 24 Alias Symbol: FBX24
Type: protein-coding gene Cytoband: 7q22.1
Entrez ID: 26261 HGNC ID: HGNC:13595 Ensembl Gene: ENSG00000106336 OMIM ID: 609097
Drug and gene relationship at DGIdb

 

Expression of FBXO24:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FBXO24 26261 223941_at -0.0391 0.9098
GSE20347 FBXO24 26261 221157_s_at -0.0823 0.1870
GSE23400 FBXO24 26261 221157_s_at -0.1243 0.0009
GSE26886 FBXO24 26261 223941_at 0.1525 0.2244
GSE29001 FBXO24 26261 221157_s_at -0.1484 0.1037
GSE38129 FBXO24 26261 221157_s_at -0.0901 0.1269
GSE45670 FBXO24 26261 223941_at -0.2024 0.0678
GSE53622 FBXO24 26261 114220 -0.7393 0.0000
GSE53624 FBXO24 26261 114220 -0.4620 0.0000
GSE63941 FBXO24 26261 223941_at 0.4795 0.0220
GSE77861 FBXO24 26261 221157_s_at 0.0316 0.8245
GSE97050 FBXO24 26261 A_33_P3237220 -0.0478 0.8653
SRP133303 FBXO24 26261 RNAseq -0.6549 0.0097
SRP159526 FBXO24 26261 RNAseq -1.0919 0.0217
SRP219564 FBXO24 26261 RNAseq -0.3748 0.5578
TCGA FBXO24 26261 RNAseq -0.0915 0.6963

Upregulated datasets: 0; Downregulated datasets: 1.  


 

Survival by FBXO24 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of FBXO24:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FBXO24 26261 13 0 17
GSE20123 FBXO24 26261 13 0 17
GSE43470 FBXO24 26261 7 2 34
GSE46452 FBXO24 26261 11 1 47
GSE47630 FBXO24 26261 7 3 30
GSE54993 FBXO24 26261 1 9 60
GSE54994 FBXO24 26261 16 3 34
GSE60625 FBXO24 26261 0 0 11
GSE74703 FBXO24 26261 7 1 28
GSE74704 FBXO24 26261 9 0 11
TCGA FBXO24 26261 53 6 37

Total number of gains: 137; Total number of losses: 25; Total Number of normals: 326.  


 

Somatic mutations of FBXO24:

 

Generating mutation plots.

 

Highly correlated genes for FBXO24:

 

Showing top 20/494 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FBXO24ESPNL0.727831404
FBXO24NAT8B0.717941303
FBXO24SBNO20.705736303
FBXO24PPP2R2B0.70422404
FBXO24BUD130.679988303
FBXO24C1orf610.677417504
FBXO24MPZ0.67426303
FBXO24SHISA80.670445303
FBXO24PRG30.665903505
FBXO24DPPA40.665892303
FBXO24NKAIN40.664496403
FBXO24HOXD90.663535403
FBXO24PADI60.662385303
FBXO24MATK0.660138403
FBXO24GRM70.656161303
FBXO24UQCRC10.654173404
FBXO24AQP60.648804605
FBXO24CHRNA100.644166403
FBXO24HSD3B10.64299505
FBXO24ACTL6B0.640617605

For details and further investigation, click here