| Full name: calcium voltage-gated channel subunit alpha1 G | Alias Symbol: Cav3.1|NBR13 | ||
| Type: protein-coding gene | Cytoband: 17q21.33 | ||
| Entrez ID: 8913 | HGNC ID: HGNC:1394 | Ensembl Gene: ENSG00000006283 | OMIM ID: 604065 |
| Drug and gene relationship at DGIdb | |||
CACNA1G involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04010 | MAPK signaling pathway | |
| hsa04020 | Calcium signaling pathway | |
| hsa04713 | Circadian entrainment | |
| hsa04930 | Type II diabetes mellitus |
Expression of CACNA1G:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CACNA1G | 8913 | 211802_x_at | -0.0173 | 0.9611 | |
| GSE20347 | CACNA1G | 8913 | 211802_x_at | -0.0010 | 0.9933 | |
| GSE23400 | CACNA1G | 8913 | 211802_x_at | -0.1709 | 0.0000 | |
| GSE26886 | CACNA1G | 8913 | 211802_x_at | -0.1055 | 0.4555 | |
| GSE29001 | CACNA1G | 8913 | 211802_x_at | -0.2289 | 0.0677 | |
| GSE38129 | CACNA1G | 8913 | 211802_x_at | -0.1259 | 0.0747 | |
| GSE45670 | CACNA1G | 8913 | 211802_x_at | -0.0541 | 0.5938 | |
| GSE53622 | CACNA1G | 8913 | 1454 | -0.4374 | 0.0000 | |
| GSE53624 | CACNA1G | 8913 | 1454 | -0.5190 | 0.0000 | |
| GSE63941 | CACNA1G | 8913 | 211802_x_at | 0.6577 | 0.0003 | |
| GSE77861 | CACNA1G | 8913 | 211802_x_at | -0.0828 | 0.2986 | |
| GSE97050 | CACNA1G | 8913 | A_23_P107247 | -0.2487 | 0.3814 | |
| SRP133303 | CACNA1G | 8913 | RNAseq | -0.8983 | 0.0231 | |
| SRP159526 | CACNA1G | 8913 | RNAseq | -1.5260 | 0.0627 | |
| SRP219564 | CACNA1G | 8913 | RNAseq | -1.8144 | 0.0179 | |
| TCGA | CACNA1G | 8913 | RNAseq | -0.2218 | 0.5891 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by CACNA1G expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CACNA1G:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CACNA1G | 8913 | 5 | 2 | 23 | |
| GSE20123 | CACNA1G | 8913 | 5 | 2 | 23 | |
| GSE43470 | CACNA1G | 8913 | 3 | 2 | 38 | |
| GSE46452 | CACNA1G | 8913 | 32 | 0 | 27 | |
| GSE47630 | CACNA1G | 8913 | 9 | 0 | 31 | |
| GSE54993 | CACNA1G | 8913 | 2 | 4 | 64 | |
| GSE54994 | CACNA1G | 8913 | 9 | 6 | 38 | |
| GSE60625 | CACNA1G | 8913 | 4 | 0 | 7 | |
| GSE74703 | CACNA1G | 8913 | 3 | 2 | 31 | |
| GSE74704 | CACNA1G | 8913 | 4 | 1 | 15 | |
| TCGA | CACNA1G | 8913 | 26 | 8 | 62 |
Total number of gains: 102; Total number of losses: 27; Total Number of normals: 359.
Somatic mutations of CACNA1G:
Generating mutation plots.
Highly correlated genes for CACNA1G:
Showing top 20/1164 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CACNA1G | PADI6 | 0.773209 | 3 | 0 | 3 |
| CACNA1G | PGC | 0.754912 | 3 | 0 | 3 |
| CACNA1G | CDC20B | 0.726368 | 3 | 0 | 3 |
| CACNA1G | MFSD2B | 0.721221 | 3 | 0 | 3 |
| CACNA1G | DGKK | 0.713805 | 4 | 0 | 4 |
| CACNA1G | LYPD8 | 0.711959 | 3 | 0 | 3 |
| CACNA1G | CCDC166 | 0.708913 | 3 | 0 | 3 |
| CACNA1G | ANHX | 0.703375 | 4 | 0 | 4 |
| CACNA1G | KLF15 | 0.702652 | 5 | 0 | 5 |
| CACNA1G | CBLN4 | 0.699652 | 4 | 0 | 4 |
| CACNA1G | OLIG3 | 0.699011 | 3 | 0 | 3 |
| CACNA1G | C20orf203 | 0.695639 | 3 | 0 | 3 |
| CACNA1G | BTBD9 | 0.694586 | 3 | 0 | 3 |
| CACNA1G | SLC5A11 | 0.687849 | 4 | 0 | 3 |
| CACNA1G | FAM163B | 0.682932 | 3 | 0 | 3 |
| CACNA1G | FAM71A | 0.681725 | 5 | 0 | 5 |
| CACNA1G | MAST4 | 0.681161 | 5 | 0 | 5 |
| CACNA1G | ABCA4 | 0.681064 | 7 | 0 | 7 |
| CACNA1G | LRRC43 | 0.6809 | 3 | 0 | 3 |
| CACNA1G | SBNO2 | 0.678561 | 4 | 0 | 4 |
For details and further investigation, click here
