PDCL3

 

Full name: phosducin like 3 Alias Symbol: VIAF1
Type: protein-coding gene Cytoband: 2q11.2
Entrez ID: 79031 HGNC ID: HGNC:28860 Ensembl Gene: ENSG00000115539 OMIM ID: 611678
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of PDCL3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 PDCL3 79031 10997 -0.0624 0.4409
GSE53624 PDCL3 79031 10997 0.1759 0.0022
GSE97050 PDCL3 79031 A_24_P80138 -0.0914 0.7696
SRP007169 PDCL3 79031 RNAseq -0.4354 0.3368
SRP008496 PDCL3 79031 RNAseq -0.2577 0.3839
SRP064894 PDCL3 79031 RNAseq 0.2526 0.2525
SRP133303 PDCL3 79031 RNAseq 0.1513 0.2684
SRP159526 PDCL3 79031 RNAseq 0.0934 0.7835
SRP193095 PDCL3 79031 RNAseq -0.2120 0.1175
SRP219564 PDCL3 79031 RNAseq -0.6762 0.0882
TCGA PDCL3 79031 RNAseq 0.2406 0.0002

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by PDCL3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of PDCL3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PDCL3 79031 5 2 23
GSE20123 PDCL3 79031 5 2 23
GSE43470 PDCL3 79031 4 1 38
GSE46452 PDCL3 79031 2 3 54
GSE47630 PDCL3 79031 7 0 33
GSE54993 PDCL3 79031 0 6 64
GSE54994 PDCL3 79031 10 0 43
GSE60625 PDCL3 79031 0 3 8
GSE74703 PDCL3 79031 4 1 31
GSE74704 PDCL3 79031 3 1 16
TCGA PDCL3 79031 33 5 58

Total number of gains: 73; Total number of losses: 24; Total Number of normals: 391.  

 

Somatic mutations of PDCL3:

 

Generating mutation plots.

 

Highly correlated genes for PDCL3:

 

Showing all 5 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PDCL3EIF5B0.700202303
PDCL3ACACA0.691963303
PDCL3TTBK20.691895303
PDCL3COX5B0.635865403
PDCL3COMMD50.634521303

For details and further investigation, click here