| Full name: COMM domain containing 5 | Alias Symbol: HT002|FLJ13008|HCaRG | ||
| Type: protein-coding gene | Cytoband: 8q24.3 | ||
| Entrez ID: 28991 | HGNC ID: HGNC:17902 | Ensembl Gene: ENSG00000170619 | OMIM ID: 608216 |
| Drug and gene relationship at DGIdb | |||
Expression of COMMD5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COMMD5 | 28991 | 224387_at | 0.7505 | 0.1045 | |
| GSE26886 | COMMD5 | 28991 | 224387_at | -0.1081 | 0.5598 | |
| GSE45670 | COMMD5 | 28991 | 224387_at | 0.1448 | 0.3649 | |
| GSE53622 | COMMD5 | 28991 | 61036 | 0.3702 | 0.0000 | |
| GSE53624 | COMMD5 | 28991 | 61036 | 0.3564 | 0.0000 | |
| GSE63941 | COMMD5 | 28991 | 224387_at | -0.7920 | 0.0961 | |
| GSE77861 | COMMD5 | 28991 | 232640_at | -0.1066 | 0.3956 | |
| GSE97050 | COMMD5 | 28991 | A_23_P20255 | 0.4206 | 0.1726 | |
| SRP007169 | COMMD5 | 28991 | RNAseq | -0.8390 | 0.0461 | |
| SRP008496 | COMMD5 | 28991 | RNAseq | -0.7571 | 0.0031 | |
| SRP064894 | COMMD5 | 28991 | RNAseq | 0.5005 | 0.0871 | |
| SRP133303 | COMMD5 | 28991 | RNAseq | 0.1863 | 0.2389 | |
| SRP159526 | COMMD5 | 28991 | RNAseq | 0.0854 | 0.6852 | |
| SRP193095 | COMMD5 | 28991 | RNAseq | 0.0133 | 0.9190 | |
| SRP219564 | COMMD5 | 28991 | RNAseq | 0.2059 | 0.5830 | |
| TCGA | COMMD5 | 28991 | RNAseq | 0.1832 | 0.0023 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by COMMD5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COMMD5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COMMD5 | 28991 | 18 | 1 | 11 | |
| GSE20123 | COMMD5 | 28991 | 18 | 1 | 11 | |
| GSE43470 | COMMD5 | 28991 | 16 | 2 | 25 | |
| GSE46452 | COMMD5 | 28991 | 28 | 0 | 31 | |
| GSE47630 | COMMD5 | 28991 | 25 | 1 | 14 | |
| GSE54993 | COMMD5 | 28991 | 0 | 25 | 45 | |
| GSE54994 | COMMD5 | 28991 | 39 | 1 | 13 | |
| GSE60625 | COMMD5 | 28991 | 3 | 4 | 4 | |
| GSE74703 | COMMD5 | 28991 | 14 | 1 | 21 | |
| GSE74704 | COMMD5 | 28991 | 11 | 0 | 9 | |
| TCGA | COMMD5 | 28991 | 63 | 2 | 31 |
Total number of gains: 235; Total number of losses: 38; Total Number of normals: 215.
Somatic mutations of COMMD5:
Generating mutation plots.
Highly correlated genes for COMMD5:
Showing top 20/336 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COMMD5 | ORC2 | 0.795966 | 3 | 0 | 3 |
| COMMD5 | PI4K2A | 0.786759 | 3 | 0 | 3 |
| COMMD5 | CBFA2T2 | 0.774559 | 3 | 0 | 3 |
| COMMD5 | ELAC2 | 0.77173 | 3 | 0 | 3 |
| COMMD5 | NCOA6 | 0.768636 | 3 | 0 | 3 |
| COMMD5 | FBXL6 | 0.766341 | 4 | 0 | 4 |
| COMMD5 | NOC2L | 0.762458 | 3 | 0 | 3 |
| COMMD5 | RBM8A | 0.761889 | 3 | 0 | 3 |
| COMMD5 | ROPN1 | 0.75936 | 3 | 0 | 3 |
| COMMD5 | GRWD1 | 0.753746 | 4 | 0 | 4 |
| COMMD5 | PLCG1 | 0.753205 | 3 | 0 | 3 |
| COMMD5 | LIMS1 | 0.750371 | 3 | 0 | 3 |
| COMMD5 | LAGE3 | 0.7443 | 4 | 0 | 4 |
| COMMD5 | PPP1R16A | 0.737216 | 4 | 0 | 4 |
| COMMD5 | LRRC42 | 0.7371 | 3 | 0 | 3 |
| COMMD5 | ZC3H3 | 0.736651 | 5 | 0 | 4 |
| COMMD5 | IGF2R | 0.736093 | 4 | 0 | 4 |
| COMMD5 | TMEM143 | 0.730658 | 3 | 0 | 3 |
| COMMD5 | C16orf58 | 0.728258 | 3 | 0 | 3 |
| COMMD5 | RBMX | 0.727929 | 3 | 0 | 3 |
For details and further investigation, click here
