PLGLB1

 

Full name: plasminogen like B1 Alias Symbol: PRP-B
Type: protein-coding gene Cytoband: 2p11.2
Entrez ID: 5343 HGNC ID: HGNC:9072 Ensembl Gene: ENSG00000183281 OMIM ID: 173340
Drug and gene relationship at DGIdb

 

Expression of PLGLB1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 PLGLB1 5343 1122 0.0692 0.6218
GSE53624 PLGLB1 5343 1122 -0.1583 0.2009
GSE97050 PLGLB1 5343 A_32_P220750 -0.0466 0.8608
SRP133303 PLGLB1 5343 RNAseq -1.3201 0.0072

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by PLGLB1 expression:

 

GSE53622GSE53624

 

Note: Click image to view full size file.  

Copy number change of PLGLB1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 PLGLB1 5343 9 2 19
GSE20123 PLGLB1 5343 9 2 19
GSE43470 PLGLB1 5343 3 2 38
GSE46452 PLGLB1 5343 2 3 54
GSE47630 PLGLB1 5343 7 0 33
GSE54993 PLGLB1 5343 0 6 64
GSE54994 PLGLB1 5343 10 0 43
GSE60625 PLGLB1 5343 0 3 8
GSE74703 PLGLB1 5343 3 1 32
GSE74704 PLGLB1 5343 7 0 13
TCGA PLGLB1 5343 35 4 57

Total number of gains: 85; Total number of losses: 23; Total Number of normals: 380.  

 

Somatic mutations of PLGLB1:

 

Generating mutation plots.

 

Highly correlated genes for PLGLB1:

 

Showing all 5 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
PLGLB1SPDYE10.697376303
PLGLB1LUC7L30.692663303
PLGLB1RGPD60.667136303
PLGLB1SPDYE50.66025303
PLGLB1TAS2R40.646882303

For details and further investigation, click here