| Full name: taste 2 receptor member 4 | Alias Symbol: T2R4 | ||
| Type: protein-coding gene | Cytoband: 7q34 | ||
| Entrez ID: 50832 | HGNC ID: HGNC:14911 | Ensembl Gene: ENSG00000127364 | OMIM ID: 604869 |
| Drug and gene relationship at DGIdb | |||
Expression of TAS2R4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TAS2R4 | 50832 | 221392_at | -0.0122 | 0.9687 | |
| GSE20347 | TAS2R4 | 50832 | 221392_at | 0.0481 | 0.6379 | |
| GSE23400 | TAS2R4 | 50832 | 221392_at | -0.0021 | 0.9664 | |
| GSE26886 | TAS2R4 | 50832 | 221392_at | -0.1065 | 0.2779 | |
| GSE29001 | TAS2R4 | 50832 | 221392_at | -0.0958 | 0.5815 | |
| GSE38129 | TAS2R4 | 50832 | 221392_at | -0.0299 | 0.7469 | |
| GSE45670 | TAS2R4 | 50832 | 221392_at | 0.0139 | 0.9111 | |
| GSE53622 | TAS2R4 | 50832 | 66868 | 0.3928 | 0.0074 | |
| GSE53624 | TAS2R4 | 50832 | 66868 | -0.0166 | 0.9207 | |
| GSE63941 | TAS2R4 | 50832 | 221392_at | 0.0521 | 0.7701 | |
| GSE77861 | TAS2R4 | 50832 | 221392_at | 0.0244 | 0.8429 | |
| GSE97050 | TAS2R4 | 50832 | A_23_P20101 | 0.2126 | 0.3956 | |
| SRP133303 | TAS2R4 | 50832 | RNAseq | -0.0687 | 0.8391 | |
| TCGA | TAS2R4 | 50832 | RNAseq | -0.7587 | 0.0966 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TAS2R4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TAS2R4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TAS2R4 | 50832 | 5 | 2 | 23 | |
| GSE20123 | TAS2R4 | 50832 | 5 | 2 | 23 | |
| GSE43470 | TAS2R4 | 50832 | 2 | 4 | 37 | |
| GSE46452 | TAS2R4 | 50832 | 7 | 2 | 50 | |
| GSE47630 | TAS2R4 | 50832 | 6 | 7 | 27 | |
| GSE54993 | TAS2R4 | 50832 | 3 | 5 | 62 | |
| GSE54994 | TAS2R4 | 50832 | 5 | 8 | 40 | |
| GSE60625 | TAS2R4 | 50832 | 0 | 0 | 11 | |
| GSE74703 | TAS2R4 | 50832 | 2 | 4 | 30 | |
| GSE74704 | TAS2R4 | 50832 | 1 | 2 | 17 | |
| TCGA | TAS2R4 | 50832 | 29 | 23 | 44 |
Total number of gains: 65; Total number of losses: 59; Total Number of normals: 364.
Somatic mutations of TAS2R4:
Generating mutation plots.
Highly correlated genes for TAS2R4:
Showing top 20/491 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TAS2R4 | MED25 | 0.788328 | 3 | 0 | 3 |
| TAS2R4 | MAPK11 | 0.75061 | 3 | 0 | 3 |
| TAS2R4 | PRKAR2A | 0.726625 | 4 | 0 | 4 |
| TAS2R4 | PRPS1L1 | 0.716387 | 5 | 0 | 5 |
| TAS2R4 | FZD4 | 0.71484 | 3 | 0 | 3 |
| TAS2R4 | GAD2 | 0.714385 | 5 | 0 | 5 |
| TAS2R4 | SLC2A5 | 0.713867 | 3 | 0 | 3 |
| TAS2R4 | VPS52 | 0.713125 | 3 | 0 | 3 |
| TAS2R4 | ABHD1 | 0.70574 | 3 | 0 | 3 |
| TAS2R4 | NXPE4 | 0.703156 | 6 | 0 | 6 |
| TAS2R4 | ZNF586 | 0.699302 | 3 | 0 | 3 |
| TAS2R4 | NTNG1 | 0.699216 | 4 | 0 | 4 |
| TAS2R4 | MAGI1 | 0.698206 | 3 | 0 | 3 |
| TAS2R4 | ZXDA | 0.697798 | 3 | 0 | 3 |
| TAS2R4 | ADAMTS9 | 0.69545 | 3 | 0 | 3 |
| TAS2R4 | ZNF681 | 0.694539 | 3 | 0 | 3 |
| TAS2R4 | GRIN2D | 0.691787 | 3 | 0 | 3 |
| TAS2R4 | FRMPD4 | 0.683203 | 4 | 0 | 4 |
| TAS2R4 | NEU3 | 0.683165 | 5 | 0 | 4 |
| TAS2R4 | GLE1 | 0.683034 | 3 | 0 | 3 |
For details and further investigation, click here
