| Full name: LUC7 like 3 pre-mRNA splicing factor | Alias Symbol: LUC7A|CROP|OA48-18|CREAP-1|FLJ11063|CRA|hLuc7A | ||
| Type: protein-coding gene | Cytoband: 17q21.33 | ||
| Entrez ID: 51747 | HGNC ID: HGNC:24309 | Ensembl Gene: ENSG00000108848 | OMIM ID: 609434 |
| Drug and gene relationship at DGIdb | |||
Expression of LUC7L3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LUC7L3 | 51747 | 220044_x_at | -0.0470 | 0.9082 | |
| GSE20347 | LUC7L3 | 51747 | 220044_x_at | 0.1329 | 0.3074 | |
| GSE23400 | LUC7L3 | 51747 | 203804_s_at | 0.3010 | 0.0016 | |
| GSE26886 | LUC7L3 | 51747 | 203804_s_at | -0.2972 | 0.2143 | |
| GSE29001 | LUC7L3 | 51747 | 203804_s_at | 0.2031 | 0.2103 | |
| GSE38129 | LUC7L3 | 51747 | 220044_x_at | 0.1957 | 0.0919 | |
| GSE45670 | LUC7L3 | 51747 | 220044_x_at | -0.1123 | 0.3932 | |
| GSE53622 | LUC7L3 | 51747 | 29510 | 0.2466 | 0.0001 | |
| GSE53624 | LUC7L3 | 51747 | 29510 | 0.4235 | 0.0000 | |
| GSE63941 | LUC7L3 | 51747 | 220044_x_at | -0.0833 | 0.8257 | |
| GSE77861 | LUC7L3 | 51747 | 203804_s_at | 0.1908 | 0.4750 | |
| GSE97050 | LUC7L3 | 51747 | A_33_P3291569 | -0.3289 | 0.2086 | |
| SRP007169 | LUC7L3 | 51747 | RNAseq | 0.8334 | 0.0391 | |
| SRP008496 | LUC7L3 | 51747 | RNAseq | 0.9148 | 0.0001 | |
| SRP064894 | LUC7L3 | 51747 | RNAseq | 0.0061 | 0.9736 | |
| SRP133303 | LUC7L3 | 51747 | RNAseq | -0.1393 | 0.2409 | |
| SRP159526 | LUC7L3 | 51747 | RNAseq | -0.1910 | 0.1294 | |
| SRP193095 | LUC7L3 | 51747 | RNAseq | -0.0056 | 0.9689 | |
| SRP219564 | LUC7L3 | 51747 | RNAseq | -0.3040 | 0.3394 | |
| TCGA | LUC7L3 | 51747 | RNAseq | -0.0833 | 0.1403 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by LUC7L3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LUC7L3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LUC7L3 | 51747 | 5 | 2 | 23 | |
| GSE20123 | LUC7L3 | 51747 | 5 | 2 | 23 | |
| GSE43470 | LUC7L3 | 51747 | 3 | 2 | 38 | |
| GSE46452 | LUC7L3 | 51747 | 32 | 0 | 27 | |
| GSE47630 | LUC7L3 | 51747 | 9 | 0 | 31 | |
| GSE54993 | LUC7L3 | 51747 | 2 | 4 | 64 | |
| GSE54994 | LUC7L3 | 51747 | 9 | 6 | 38 | |
| GSE60625 | LUC7L3 | 51747 | 4 | 0 | 7 | |
| GSE74703 | LUC7L3 | 51747 | 3 | 2 | 31 | |
| GSE74704 | LUC7L3 | 51747 | 4 | 1 | 15 | |
| TCGA | LUC7L3 | 51747 | 26 | 8 | 62 |
Total number of gains: 102; Total number of losses: 27; Total Number of normals: 359.
Somatic mutations of LUC7L3:
Generating mutation plots.
Highly correlated genes for LUC7L3:
Showing top 20/300 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LUC7L3 | ZNF223 | 0.808518 | 3 | 0 | 3 |
| LUC7L3 | MLLT6 | 0.787536 | 3 | 0 | 3 |
| LUC7L3 | TRIM56 | 0.784718 | 3 | 0 | 3 |
| LUC7L3 | FAM193B | 0.783442 | 3 | 0 | 3 |
| LUC7L3 | ZFP62 | 0.764914 | 3 | 0 | 3 |
| LUC7L3 | SIPA1L2 | 0.755014 | 3 | 0 | 3 |
| LUC7L3 | ACAD11 | 0.728349 | 3 | 0 | 3 |
| LUC7L3 | INPP4A | 0.725746 | 3 | 0 | 3 |
| LUC7L3 | SLC26A11 | 0.725147 | 3 | 0 | 3 |
| LUC7L3 | FAM120B | 0.723823 | 3 | 0 | 3 |
| LUC7L3 | DHX40 | 0.71752 | 4 | 0 | 4 |
| LUC7L3 | SPDYE1 | 0.717208 | 3 | 0 | 3 |
| LUC7L3 | CLASRP | 0.714555 | 3 | 0 | 3 |
| LUC7L3 | ZNF573 | 0.709612 | 3 | 0 | 3 |
| LUC7L3 | EPC1 | 0.704319 | 3 | 0 | 3 |
| LUC7L3 | ZNF514 | 0.703677 | 3 | 0 | 3 |
| LUC7L3 | ZNF506 | 0.703645 | 3 | 0 | 3 |
| LUC7L3 | PAN3 | 0.702854 | 5 | 0 | 4 |
| LUC7L3 | TAS2R43 | 0.701332 | 3 | 0 | 3 |
| LUC7L3 | DIS3L2 | 0.701323 | 3 | 0 | 3 |
For details and further investigation, click here
