RPL21

 

Full name: ribosomal protein L21 Alias Symbol: L21|FLJ27458|MGC71252|MGC104274|MGC104275|DKFZp686C06101
Type: protein-coding gene Cytoband: 13q12.2
Entrez ID: 6144 HGNC ID: HGNC:10313 Ensembl Gene: ENSG00000122026 OMIM ID: 603636
Drug and gene relationship at DGIdb

 

Expression of RPL21:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE53622 RPL21 6144 48752 -0.6208 0.0000
GSE53624 RPL21 6144 48752 -0.3127 0.0000
GSE97050 RPL21 6144 A_32_P184518 -0.5190 0.1834
SRP007169 RPL21 6144 RNAseq -1.5038 0.0000
SRP008496 RPL21 6144 RNAseq -1.1633 0.0000
SRP064894 RPL21 6144 RNAseq -0.2285 0.5094
SRP133303 RPL21 6144 RNAseq -0.6171 0.0004
SRP159526 RPL21 6144 RNAseq -1.0093 0.0028
SRP193095 RPL21 6144 RNAseq -1.1704 0.0000
SRP219564 RPL21 6144 RNAseq -0.8270 0.0432
TCGA RPL21 6144 RNAseq 0.7322 0.1553

Upregulated datasets: 0; Downregulated datasets: 4.  

 

Survival by RPL21 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of RPL21:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 RPL21 6144 1 13 16
GSE20123 RPL21 6144 1 12 17
GSE43470 RPL21 6144 2 12 29
GSE46452 RPL21 6144 0 33 26
GSE47630 RPL21 6144 3 26 11
GSE54993 RPL21 6144 11 2 57
GSE54994 RPL21 6144 1 13 39
GSE60625 RPL21 6144 0 3 8
GSE74703 RPL21 6144 2 9 25
GSE74704 RPL21 6144 0 10 10
TCGA RPL21 6144 6 41 49

Total number of gains: 27; Total number of losses: 174; Total Number of normals: 287.  

 

Somatic mutations of RPL21:

 

Generating mutation plots.

 

Highly correlated genes for RPL21:

 

Showing all 10 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
RPL21RPS15A0.718567303
RPL21RPS250.675896404
RPL21RPL220.674954403
RPL21RPL90.648246403
RPL21RPL150.647347303
RPL21RPS120.645663403
RPL21RPL290.634809303
RPL21RPL310.625029403
RPL21COX8A0.615305303
RPL21RPL70.564433303

For details and further investigation, click here