| Full name: ribosomal protein L15 | Alias Symbol: RPL10|RPLY10|RPYL10|EC45|L15 | ||
| Type: protein-coding gene | Cytoband: 3p24.2 | ||
| Entrez ID: 6138 | HGNC ID: HGNC:10306 | Ensembl Gene: ENSG00000174748 | OMIM ID: 604174 |
| Drug and gene relationship at DGIdb | |||
Expression of RPL15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL15 | 6138 | 221475_s_at | -0.1079 | 0.5717 | |
| GSE20347 | RPL15 | 6138 | 221475_s_at | -0.3349 | 0.0077 | |
| GSE23400 | RPL15 | 6138 | 221475_s_at | -0.1609 | 0.0637 | |
| GSE26886 | RPL15 | 6138 | 221475_s_at | 0.2186 | 0.0846 | |
| GSE29001 | RPL15 | 6138 | 221475_s_at | -0.5314 | 0.1377 | |
| GSE38129 | RPL15 | 6138 | 221475_s_at | -0.2286 | 0.0108 | |
| GSE45670 | RPL15 | 6138 | 221475_s_at | -0.3461 | 0.0011 | |
| GSE53622 | RPL15 | 6138 | 30812 | -0.5581 | 0.0000 | |
| GSE53624 | RPL15 | 6138 | 30812 | -0.4602 | 0.0000 | |
| GSE63941 | RPL15 | 6138 | 221475_s_at | 0.3592 | 0.0708 | |
| GSE77861 | RPL15 | 6138 | 221475_s_at | -0.3805 | 0.0956 | |
| GSE97050 | RPL15 | 6138 | A_24_P257359 | -0.5680 | 0.1321 | |
| SRP007169 | RPL15 | 6138 | RNAseq | -1.2913 | 0.0001 | |
| SRP008496 | RPL15 | 6138 | RNAseq | -1.0363 | 0.0000 | |
| SRP064894 | RPL15 | 6138 | RNAseq | -0.7714 | 0.0011 | |
| SRP133303 | RPL15 | 6138 | RNAseq | -0.8093 | 0.0000 | |
| SRP159526 | RPL15 | 6138 | RNAseq | -0.9268 | 0.0005 | |
| SRP193095 | RPL15 | 6138 | RNAseq | -1.1905 | 0.0000 | |
| SRP219564 | RPL15 | 6138 | RNAseq | -0.9161 | 0.0026 | |
| TCGA | RPL15 | 6138 | RNAseq | -0.1398 | 0.0002 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RPL15 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL15 | 6138 | 0 | 18 | 12 | |
| GSE20123 | RPL15 | 6138 | 0 | 18 | 12 | |
| GSE43470 | RPL15 | 6138 | 0 | 20 | 23 | |
| GSE46452 | RPL15 | 6138 | 2 | 17 | 40 | |
| GSE47630 | RPL15 | 6138 | 1 | 24 | 15 | |
| GSE54993 | RPL15 | 6138 | 6 | 2 | 62 | |
| GSE54994 | RPL15 | 6138 | 1 | 32 | 20 | |
| GSE60625 | RPL15 | 6138 | 5 | 0 | 6 | |
| GSE74703 | RPL15 | 6138 | 0 | 17 | 19 | |
| GSE74704 | RPL15 | 6138 | 0 | 12 | 8 | |
| TCGA | RPL15 | 6138 | 0 | 69 | 27 |
Total number of gains: 15; Total number of losses: 229; Total Number of normals: 244.
Somatic mutations of RPL15:
Generating mutation plots.
Highly correlated genes for RPL15:
Showing top 20/351 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL15 | RPL29 | 0.783555 | 12 | 0 | 12 |
| RPL15 | RPL3 | 0.746237 | 10 | 0 | 9 |
| RPL15 | RPL14 | 0.691947 | 9 | 0 | 7 |
| RPL15 | RPL32 | 0.686056 | 13 | 0 | 11 |
| RPL15 | EEF1A1 | 0.677501 | 8 | 0 | 7 |
| RPL15 | IMPDH2 | 0.665497 | 9 | 0 | 7 |
| RPL15 | RPS6 | 0.662198 | 11 | 0 | 9 |
| RPL15 | RPS8 | 0.661808 | 4 | 0 | 3 |
| RPL15 | RPL10A | 0.651075 | 12 | 0 | 9 |
| RPL15 | RPL31 | 0.649333 | 11 | 0 | 10 |
| RPL15 | BTF3 | 0.648404 | 11 | 0 | 10 |
| RPL15 | RPS18 | 0.648348 | 12 | 0 | 10 |
| RPL15 | RPS14 | 0.647816 | 13 | 0 | 12 |
| RPL15 | RNF125 | 0.647788 | 4 | 0 | 4 |
| RPL15 | RPL21 | 0.647347 | 3 | 0 | 3 |
| RPL15 | RPS3 | 0.646248 | 6 | 0 | 5 |
| RPL15 | BRK1 | 0.646245 | 6 | 0 | 4 |
| RPL15 | RPL18 | 0.644772 | 12 | 0 | 10 |
| RPL15 | FBXO32 | 0.641939 | 3 | 0 | 3 |
| RPL15 | RPS3A | 0.641262 | 4 | 0 | 3 |
For details and further investigation, click here
