| Full name: ribosomal protein S12 | Alias Symbol: S12 | ||
| Type: protein-coding gene | Cytoband: 6q23.2 | ||
| Entrez ID: 6206 | HGNC ID: HGNC:10385 | Ensembl Gene: ENSG00000112306 | OMIM ID: 603660 |
| Drug and gene relationship at DGIdb | |||
Expression of RPS12:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPS12 | 6206 | 213377_x_at | -0.1461 | 0.6351 | |
| GSE20347 | RPS12 | 6206 | 213377_x_at | -0.1987 | 0.1867 | |
| GSE23400 | RPS12 | 6206 | 213377_x_at | -0.1516 | 0.0081 | |
| GSE26886 | RPS12 | 6206 | 213377_x_at | -0.1987 | 0.0681 | |
| GSE29001 | RPS12 | 6206 | 213377_x_at | -0.3017 | 0.3202 | |
| GSE38129 | RPS12 | 6206 | 213377_x_at | -0.1332 | 0.1920 | |
| GSE45670 | RPS12 | 6206 | 213377_x_at | -0.2354 | 0.0029 | |
| GSE53622 | RPS12 | 6206 | 57604 | -0.7085 | 0.0000 | |
| GSE53624 | RPS12 | 6206 | 57604 | -0.3206 | 0.0005 | |
| GSE63941 | RPS12 | 6206 | 213377_x_at | 0.0731 | 0.7592 | |
| GSE77861 | RPS12 | 6206 | 213377_x_at | -0.2088 | 0.3858 | |
| GSE97050 | RPS12 | 6206 | A_23_P82128 | -0.3583 | 0.3054 | |
| SRP007169 | RPS12 | 6206 | RNAseq | -1.3294 | 0.0001 | |
| SRP008496 | RPS12 | 6206 | RNAseq | -1.2366 | 0.0000 | |
| SRP064894 | RPS12 | 6206 | RNAseq | -0.5009 | 0.1313 | |
| SRP133303 | RPS12 | 6206 | RNAseq | -0.6932 | 0.0000 | |
| SRP159526 | RPS12 | 6206 | RNAseq | -0.8450 | 0.0170 | |
| SRP193095 | RPS12 | 6206 | RNAseq | -1.1756 | 0.0000 | |
| SRP219564 | RPS12 | 6206 | RNAseq | -0.7520 | 0.0000 | |
| TCGA | RPS12 | 6206 | RNAseq | -0.0040 | 0.9485 |
Upregulated datasets: 0; Downregulated datasets: 3.
Survival by RPS12 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPS12:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPS12 | 6206 | 3 | 4 | 23 | |
| GSE20123 | RPS12 | 6206 | 3 | 3 | 24 | |
| GSE43470 | RPS12 | 6206 | 5 | 0 | 38 | |
| GSE46452 | RPS12 | 6206 | 2 | 11 | 46 | |
| GSE47630 | RPS12 | 6206 | 9 | 4 | 27 | |
| GSE54993 | RPS12 | 6206 | 3 | 2 | 65 | |
| GSE54994 | RPS12 | 6206 | 9 | 7 | 37 | |
| GSE60625 | RPS12 | 6206 | 0 | 1 | 10 | |
| GSE74703 | RPS12 | 6206 | 4 | 0 | 32 | |
| GSE74704 | RPS12 | 6206 | 1 | 1 | 18 | |
| TCGA | RPS12 | 6206 | 11 | 18 | 67 |
Total number of gains: 50; Total number of losses: 51; Total Number of normals: 387.
Somatic mutations of RPS12:
Generating mutation plots.
Highly correlated genes for RPS12:
Showing top 20/134 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPS12 | RPL10A | 0.654858 | 10 | 0 | 7 |
| RPS12 | RPL21 | 0.645663 | 4 | 0 | 3 |
| RPS12 | PFDN5 | 0.642221 | 7 | 0 | 7 |
| RPS12 | RPS6 | 0.637813 | 9 | 0 | 7 |
| RPS12 | EEF1A1 | 0.637532 | 10 | 0 | 7 |
| RPS12 | CDKN1B | 0.622162 | 4 | 0 | 4 |
| RPS12 | GPR27 | 0.620774 | 3 | 0 | 3 |
| RPS12 | RPS5 | 0.616611 | 11 | 0 | 9 |
| RPS12 | FOXA1 | 0.614559 | 3 | 0 | 3 |
| RPS12 | NACA | 0.614444 | 9 | 0 | 8 |
| RPS12 | BTC | 0.614318 | 4 | 0 | 4 |
| RPS12 | RPL6 | 0.613689 | 9 | 0 | 8 |
| RPS12 | SIAH2 | 0.612693 | 3 | 0 | 3 |
| RPS12 | NHP2 | 0.612123 | 9 | 0 | 7 |
| RPS12 | RPL9 | 0.611346 | 12 | 0 | 9 |
| RPS12 | LAMTOR5 | 0.610523 | 6 | 0 | 4 |
| RPS12 | ELN | 0.609784 | 4 | 0 | 3 |
| RPS12 | PDK4 | 0.609572 | 4 | 0 | 3 |
| RPS12 | RPS14 | 0.609455 | 8 | 0 | 7 |
| RPS12 | ATP1A2 | 0.607175 | 3 | 0 | 3 |
For details and further investigation, click here
