| Full name: ribosomal protein L7 | Alias Symbol: humL7-1|L7 | ||
| Type: protein-coding gene | Cytoband: 8q21.11 | ||
| Entrez ID: 6129 | HGNC ID: HGNC:10363 | Ensembl Gene: ENSG00000147604 | OMIM ID: 604166 |
| Drug and gene relationship at DGIdb | |||
Expression of RPL7:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RPL7 | 6129 | 200717_x_at | 0.0796 | 0.7208 | |
| GSE20347 | RPL7 | 6129 | 200717_x_at | 0.1525 | 0.0289 | |
| GSE23400 | RPL7 | 6129 | 200717_x_at | 0.1002 | 0.0288 | |
| GSE26886 | RPL7 | 6129 | 200717_x_at | 0.0665 | 0.4974 | |
| GSE29001 | RPL7 | 6129 | 200717_x_at | -0.0366 | 0.9162 | |
| GSE38129 | RPL7 | 6129 | 200717_x_at | 0.1073 | 0.0701 | |
| GSE45670 | RPL7 | 6129 | 200717_x_at | -0.0655 | 0.2968 | |
| GSE53622 | RPL7 | 6129 | 7111 | 0.0886 | 0.2477 | |
| GSE53624 | RPL7 | 6129 | 7111 | 0.1457 | 0.0323 | |
| GSE63941 | RPL7 | 6129 | 200717_x_at | 0.0533 | 0.8218 | |
| GSE77861 | RPL7 | 6129 | 200717_x_at | -0.0721 | 0.6521 | |
| GSE97050 | RPL7 | 6129 | A_33_P3370226 | -0.0025 | 0.9926 | |
| SRP007169 | RPL7 | 6129 | RNAseq | -0.5729 | 0.1377 | |
| SRP008496 | RPL7 | 6129 | RNAseq | -0.4321 | 0.0654 | |
| SRP064894 | RPL7 | 6129 | RNAseq | -0.1294 | 0.6400 | |
| SRP133303 | RPL7 | 6129 | RNAseq | -0.4502 | 0.0001 | |
| SRP159526 | RPL7 | 6129 | RNAseq | -0.5148 | 0.0348 | |
| SRP193095 | RPL7 | 6129 | RNAseq | -0.9401 | 0.0000 | |
| SRP219564 | RPL7 | 6129 | RNAseq | -0.1973 | 0.6062 | |
| TCGA | RPL7 | 6129 | RNAseq | 0.2010 | 0.1649 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by RPL7 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RPL7:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RPL7 | 6129 | 15 | 0 | 15 | |
| GSE20123 | RPL7 | 6129 | 16 | 0 | 14 | |
| GSE43470 | RPL7 | 6129 | 18 | 1 | 24 | |
| GSE46452 | RPL7 | 6129 | 21 | 1 | 37 | |
| GSE47630 | RPL7 | 6129 | 23 | 0 | 17 | |
| GSE54993 | RPL7 | 6129 | 0 | 19 | 51 | |
| GSE54994 | RPL7 | 6129 | 30 | 0 | 23 | |
| GSE60625 | RPL7 | 6129 | 0 | 4 | 7 | |
| GSE74703 | RPL7 | 6129 | 15 | 1 | 20 | |
| GSE74704 | RPL7 | 6129 | 11 | 0 | 9 | |
| TCGA | RPL7 | 6129 | 50 | 2 | 44 |
Total number of gains: 199; Total number of losses: 28; Total Number of normals: 261.
Somatic mutations of RPL7:
Generating mutation plots.
Highly correlated genes for RPL7:
Showing top 20/51 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RPL7 | RPL30 | 0.695767 | 10 | 0 | 9 |
| RPL7 | ZNF337 | 0.661188 | 3 | 0 | 3 |
| RPL7 | ZNF30 | 0.646889 | 3 | 0 | 3 |
| RPL7 | ZNF133 | 0.624437 | 3 | 0 | 3 |
| RPL7 | CCDC122 | 0.623971 | 3 | 0 | 3 |
| RPL7 | SYF2 | 0.621754 | 4 | 0 | 4 |
| RPL7 | ABT1 | 0.620057 | 4 | 0 | 4 |
| RPL7 | ZNF711 | 0.612896 | 5 | 0 | 4 |
| RPL7 | TUSC1 | 0.605874 | 3 | 0 | 3 |
| RPL7 | PHF10 | 0.595638 | 6 | 0 | 4 |
| RPL7 | USP30 | 0.593462 | 3 | 0 | 3 |
| RPL7 | COX7A2 | 0.591659 | 4 | 0 | 3 |
| RPL7 | TAF4 | 0.590407 | 5 | 0 | 3 |
| RPL7 | IDH3B | 0.584609 | 3 | 0 | 3 |
| RPL7 | NHP2 | 0.583533 | 4 | 0 | 3 |
| RPL7 | ZC3H8 | 0.571213 | 4 | 0 | 3 |
| RPL7 | RPS15A | 0.570177 | 11 | 0 | 7 |
| RPL7 | PAN3-AS1 | 0.568101 | 4 | 0 | 3 |
| RPL7 | ARFGEF1 | 0.566413 | 10 | 0 | 6 |
| RPL7 | RPL21 | 0.564433 | 3 | 0 | 3 |
For details and further investigation, click here
