SLFN13

 

Full name: schlafen family member 13 Alias Symbol: FLJ31952
Type: protein-coding gene Cytoband: 17q12
Entrez ID: 146857 HGNC ID: HGNC:26481 Ensembl Gene: ENSG00000154760 OMIM ID: 614957
Drug and gene relationship at DGIdb

 

Expression of SLFN13:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SLFN13 146857 1558217_at 0.4633 0.5509
GSE26886 SLFN13 146857 1558217_at 0.1657 0.5254
GSE45670 SLFN13 146857 1558217_at 0.1165 0.7297
GSE53622 SLFN13 146857 75157 -0.3233 0.0275
GSE53624 SLFN13 146857 75157 -0.6257 0.0000
GSE63941 SLFN13 146857 1558217_at 0.7071 0.3642
GSE77861 SLFN13 146857 1558217_at -0.1676 0.4539
SRP007169 SLFN13 146857 RNAseq 2.0143 0.0010
SRP064894 SLFN13 146857 RNAseq -0.2249 0.5506
SRP133303 SLFN13 146857 RNAseq 0.3540 0.3451
SRP159526 SLFN13 146857 RNAseq -0.2899 0.7186
SRP193095 SLFN13 146857 RNAseq -0.0023 0.9903
SRP219564 SLFN13 146857 RNAseq -0.9953 0.0073
TCGA SLFN13 146857 RNAseq -0.0733 0.6969

Upregulated datasets: 1; Downregulated datasets: 0.  

 

Survival by SLFN13 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of SLFN13:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SLFN13 146857 5 1 24
GSE20123 SLFN13 146857 5 1 24
GSE43470 SLFN13 146857 1 2 40
GSE46452 SLFN13 146857 34 0 25
GSE47630 SLFN13 146857 7 1 32
GSE54993 SLFN13 146857 3 3 64
GSE54994 SLFN13 146857 8 6 39
GSE60625 SLFN13 146857 4 0 7
GSE74703 SLFN13 146857 1 1 34
GSE74704 SLFN13 146857 3 1 16
TCGA SLFN13 146857 20 9 67

Total number of gains: 91; Total number of losses: 25; Total Number of normals: 372.  

 

Somatic mutations of SLFN13:

 

Generating mutation plots.

 

Highly correlated genes for SLFN13:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SLFN13ATG16L20.62493403
SLFN13LINC013050.6009403
SLFN13FGFR30.553045504
SLFN13SULT1E10.543264303
SLFN13NAIP0.535954303
SLFN13SSH30.519578503

For details and further investigation, click here