| Full name: autophagy related 16 like 2 | Alias Symbol: FLJ00012|WDR80|ATG16B | ||
| Type: protein-coding gene | Cytoband: 11q13.4 | ||
| Entrez ID: 89849 | HGNC ID: HGNC:25464 | Ensembl Gene: ENSG00000168010 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of ATG16L2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ATG16L2 | 89849 | 225883_at | 0.2414 | 0.6625 | |
| GSE26886 | ATG16L2 | 89849 | 225883_at | -0.8939 | 0.0035 | |
| GSE45670 | ATG16L2 | 89849 | 225883_at | -0.0284 | 0.9057 | |
| GSE53622 | ATG16L2 | 89849 | 41516 | -0.5318 | 0.0000 | |
| GSE53624 | ATG16L2 | 89849 | 41516 | -0.6586 | 0.0000 | |
| GSE63941 | ATG16L2 | 89849 | 225883_at | 0.2667 | 0.2950 | |
| GSE77861 | ATG16L2 | 89849 | 229389_at | -0.0791 | 0.8249 | |
| GSE97050 | ATG16L2 | 89849 | A_23_P36305 | -0.0184 | 0.9425 | |
| SRP007169 | ATG16L2 | 89849 | RNAseq | -0.3916 | 0.4666 | |
| SRP064894 | ATG16L2 | 89849 | RNAseq | -0.3217 | 0.0942 | |
| SRP133303 | ATG16L2 | 89849 | RNAseq | -0.6381 | 0.0024 | |
| SRP159526 | ATG16L2 | 89849 | RNAseq | -1.4737 | 0.0000 | |
| SRP193095 | ATG16L2 | 89849 | RNAseq | -0.1346 | 0.5551 | |
| SRP219564 | ATG16L2 | 89849 | RNAseq | -0.8457 | 0.0154 | |
| TCGA | ATG16L2 | 89849 | RNAseq | -0.2372 | 0.0216 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ATG16L2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ATG16L2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ATG16L2 | 89849 | 10 | 6 | 14 | |
| GSE20123 | ATG16L2 | 89849 | 10 | 6 | 14 | |
| GSE43470 | ATG16L2 | 89849 | 9 | 3 | 31 | |
| GSE46452 | ATG16L2 | 89849 | 10 | 19 | 30 | |
| GSE47630 | ATG16L2 | 89849 | 8 | 12 | 20 | |
| GSE54993 | ATG16L2 | 89849 | 8 | 2 | 60 | |
| GSE54994 | ATG16L2 | 89849 | 9 | 15 | 29 | |
| GSE60625 | ATG16L2 | 89849 | 0 | 7 | 4 | |
| GSE74703 | ATG16L2 | 89849 | 7 | 2 | 27 | |
| GSE74704 | ATG16L2 | 89849 | 7 | 3 | 10 | |
| TCGA | ATG16L2 | 89849 | 32 | 24 | 40 |
Total number of gains: 110; Total number of losses: 99; Total Number of normals: 279.
Somatic mutations of ATG16L2:
Generating mutation plots.
Highly correlated genes for ATG16L2:
Showing top 20/59 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ATG16L2 | NKTR | 0.669843 | 3 | 0 | 3 |
| ATG16L2 | ARHGEF10L | 0.648399 | 3 | 0 | 3 |
| ATG16L2 | USO1 | 0.648283 | 3 | 0 | 3 |
| ATG16L2 | APH1A | 0.641946 | 3 | 0 | 3 |
| ATG16L2 | ARAP1 | 0.637307 | 4 | 0 | 3 |
| ATG16L2 | B3GALNT1 | 0.636074 | 4 | 0 | 3 |
| ATG16L2 | SLFN13 | 0.62493 | 4 | 0 | 3 |
| ATG16L2 | EED | 0.615769 | 3 | 0 | 3 |
| ATG16L2 | NAAA | 0.612574 | 3 | 0 | 3 |
| ATG16L2 | EXOC1 | 0.608201 | 4 | 0 | 3 |
| ATG16L2 | ECHS1 | 0.59672 | 4 | 0 | 3 |
| ATG16L2 | STARD10 | 0.591397 | 5 | 0 | 3 |
| ATG16L2 | FAM3D | 0.590883 | 4 | 0 | 3 |
| ATG16L2 | KIAA2026 | 0.583457 | 3 | 0 | 3 |
| ATG16L2 | SARS2 | 0.583256 | 3 | 0 | 3 |
| ATG16L2 | PLEKHN1 | 0.580181 | 4 | 0 | 4 |
| ATG16L2 | ZFAND2B | 0.577516 | 4 | 0 | 4 |
| ATG16L2 | AHNAK | 0.572678 | 3 | 0 | 3 |
| ATG16L2 | TJP3 | 0.567954 | 3 | 0 | 3 |
| ATG16L2 | EPHA2 | 0.564956 | 3 | 0 | 3 |
For details and further investigation, click here
