SULT1E1

 

Full name: sulfotransferase family 1E member 1 Alias Symbol: EST
Type: protein-coding gene Cytoband: 4q13.3
Entrez ID: 6783 HGNC ID: HGNC:11377 Ensembl Gene: ENSG00000109193 OMIM ID: 600043
Screen Evidence:
  • Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

 

Expression of SULT1E1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SULT1E1 6783 219934_s_at 1.0555 0.3102
GSE20347 SULT1E1 6783 219934_s_at 0.5163 0.0707
GSE23400 SULT1E1 6783 219934_s_at 0.0302 0.6858
GSE26886 SULT1E1 6783 219934_s_at 1.3921 0.0098
GSE29001 SULT1E1 6783 219934_s_at 0.5095 0.0460
GSE38129 SULT1E1 6783 219934_s_at 0.3634 0.0745
GSE45670 SULT1E1 6783 219934_s_at 0.5767 0.0480
GSE53622 SULT1E1 6783 154146 1.5206 0.0001
GSE53624 SULT1E1 6783 154146 1.3207 0.0000
GSE63941 SULT1E1 6783 219934_s_at 0.7118 0.3833
GSE77861 SULT1E1 6783 219934_s_at 0.0611 0.7105
SRP133303 SULT1E1 6783 RNAseq 2.6466 0.0000
SRP159526 SULT1E1 6783 RNAseq 4.1093 0.0000
TCGA SULT1E1 6783 RNAseq -0.0174 0.9796

Upregulated datasets: 5; Downregulated datasets: 0.  


 

Survival by SULT1E1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SULT1E1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SULT1E1 6783 0 10 20
GSE20123 SULT1E1 6783 0 11 19
GSE43470 SULT1E1 6783 0 13 30
GSE46452 SULT1E1 6783 2 35 22
GSE47630 SULT1E1 6783 1 18 21
GSE54993 SULT1E1 6783 7 0 63
GSE54994 SULT1E1 6783 1 9 43
GSE60625 SULT1E1 6783 0 0 11
GSE74703 SULT1E1 6783 0 11 25
GSE74704 SULT1E1 6783 0 7 13
TCGA SULT1E1 6783 15 28 53

Total number of gains: 26; Total number of losses: 142; Total Number of normals: 320.  


 

Somatic mutations of SULT1E1:

 

Generating mutation plots.

 

Highly correlated genes for SULT1E1:

 

Showing top 20/62 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SULT1E1LYPD10.750444303
SULT1E1ADAMTS30.734075403
SULT1E1FGF30.692757303
SULT1E1VTCN10.680009403
SULT1E1PHIP0.670809303
SULT1E1ATP8A20.661917303
SULT1E1SLC7A80.658803303
SULT1E1NGFR0.646443403
SULT1E1DZANK10.64498404
SULT1E1RNMT0.623498303
SULT1E1TNFRSF11B0.621701403
SULT1E1HOXB130.618747403
SULT1E1LAMA50.611436403
SULT1E1PINLYP0.604874303
SULT1E1TANK0.597243403
SULT1E1PTHLH0.59359303
SULT1E1ODAM0.589739503
SULT1E1IGF2BP20.585787503
SULT1E1HOXD90.585471403
SULT1E1ZIC20.581288503

For details and further investigation, click here