VWA3B

 

Full name: von Willebrand factor A domain containing 3B Alias Symbol: DKFZp686F2227|MGC26733
Type: protein-coding gene Cytoband: 2q11.2
Entrez ID: 200403 HGNC ID: HGNC:28385 Ensembl Gene: ENSG00000168658 OMIM ID: 614884
Drug and gene relationship at DGIdb

 

Expression of VWA3B:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 VWA3B 200403 1564598_a_at -0.0443 0.8580
GSE26886 VWA3B 200403 1564598_a_at 0.1216 0.2879
GSE45670 VWA3B 200403 1564598_a_at -0.0746 0.4627
GSE53622 VWA3B 200403 7777 0.3071 0.2559
GSE53624 VWA3B 200403 16149 -0.1135 0.0715
GSE63941 VWA3B 200403 1564598_a_at 0.0746 0.6029
GSE77861 VWA3B 200403 1558470_at -0.0400 0.7708
TCGA VWA3B 200403 RNAseq -1.6098 0.0145

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by VWA3B expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of VWA3B:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 VWA3B 200403 6 2 22
GSE20123 VWA3B 200403 6 2 22
GSE43470 VWA3B 200403 3 2 38
GSE46452 VWA3B 200403 2 3 54
GSE47630 VWA3B 200403 7 0 33
GSE54993 VWA3B 200403 0 6 64
GSE54994 VWA3B 200403 11 0 42
GSE60625 VWA3B 200403 0 3 8
GSE74703 VWA3B 200403 3 2 31
GSE74704 VWA3B 200403 4 1 15
TCGA VWA3B 200403 34 4 58

Total number of gains: 76; Total number of losses: 25; Total Number of normals: 387.  

 

Somatic mutations of VWA3B:

 

Generating mutation plots.

 

Highly correlated genes for VWA3B:

 

Showing all 9 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
VWA3BRS10.685584404
VWA3BMRGPRX40.615206303
VWA3BSPATA80.611877303
VWA3BC8orf740.58274403
VWA3BSLC6A200.557614303
VWA3BRXFP30.5516303
VWA3BOR4D10.53332403
VWA3BGTF3C2-AS10.526358403
VWA3BTFAP2D0.506417403

For details and further investigation, click here