| Full name: relaxin family peptide receptor 3 | Alias Symbol: SALPR|GPCR135|RXFPR3 | ||
| Type: protein-coding gene | Cytoband: 5p13.2 | ||
| Entrez ID: 51289 | HGNC ID: HGNC:24883 | Ensembl Gene: ENSG00000182631 | OMIM ID: 609445 |
| Drug and gene relationship at DGIdb | |||
Expression of RXFP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | RXFP3 | 51289 | 221066_at | -0.3448 | 0.1946 | |
| GSE20347 | RXFP3 | 51289 | 221066_at | -0.2884 | 0.0000 | |
| GSE23400 | RXFP3 | 51289 | 221066_at | -0.1238 | 0.0000 | |
| GSE26886 | RXFP3 | 51289 | 221066_at | -0.1046 | 0.4628 | |
| GSE29001 | RXFP3 | 51289 | 221066_at | -0.3679 | 0.0027 | |
| GSE38129 | RXFP3 | 51289 | 221066_at | -0.1812 | 0.0002 | |
| GSE45670 | RXFP3 | 51289 | 221066_at | -0.0358 | 0.7249 | |
| GSE53622 | RXFP3 | 51289 | 90777 | 0.0260 | 0.7995 | |
| GSE53624 | RXFP3 | 51289 | 90777 | 0.1203 | 0.4734 | |
| GSE63941 | RXFP3 | 51289 | 221066_at | -0.1913 | 0.2752 | |
| GSE77861 | RXFP3 | 51289 | 221066_at | -0.2782 | 0.0306 | |
| GSE97050 | RXFP3 | 51289 | A_23_P363365 | -0.0350 | 0.8913 | |
| TCGA | RXFP3 | 51289 | RNAseq | 3.2218 | 0.0006 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by RXFP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of RXFP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | RXFP3 | 51289 | 11 | 0 | 19 | |
| GSE20123 | RXFP3 | 51289 | 11 | 0 | 19 | |
| GSE43470 | RXFP3 | 51289 | 15 | 3 | 25 | |
| GSE46452 | RXFP3 | 51289 | 6 | 21 | 32 | |
| GSE47630 | RXFP3 | 51289 | 6 | 12 | 22 | |
| GSE54993 | RXFP3 | 51289 | 5 | 4 | 61 | |
| GSE54994 | RXFP3 | 51289 | 26 | 2 | 25 | |
| GSE60625 | RXFP3 | 51289 | 0 | 0 | 11 | |
| GSE74703 | RXFP3 | 51289 | 12 | 2 | 22 | |
| GSE74704 | RXFP3 | 51289 | 10 | 0 | 10 | |
| TCGA | RXFP3 | 51289 | 51 | 6 | 39 |
Total number of gains: 153; Total number of losses: 50; Total Number of normals: 285.
Somatic mutations of RXFP3:
Generating mutation plots.
Highly correlated genes for RXFP3:
Showing top 20/803 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| RXFP3 | PLA2G2C | 0.797368 | 3 | 0 | 3 |
| RXFP3 | STRC | 0.794131 | 3 | 0 | 3 |
| RXFP3 | IL1F10 | 0.76945 | 3 | 0 | 3 |
| RXFP3 | F2RL3 | 0.758772 | 3 | 0 | 3 |
| RXFP3 | OR4D6 | 0.757502 | 3 | 0 | 3 |
| RXFP3 | NT5C1A | 0.752704 | 4 | 0 | 4 |
| RXFP3 | PNMA6A | 0.745307 | 3 | 0 | 3 |
| RXFP3 | OR2T27 | 0.738142 | 3 | 0 | 3 |
| RXFP3 | KRTAP10-12 | 0.737588 | 3 | 0 | 3 |
| RXFP3 | DCDC1 | 0.736337 | 3 | 0 | 3 |
| RXFP3 | ACR | 0.734508 | 4 | 0 | 4 |
| RXFP3 | OR2A5 | 0.732145 | 3 | 0 | 3 |
| RXFP3 | KCNK5 | 0.729186 | 3 | 0 | 3 |
| RXFP3 | TMEM37 | 0.728599 | 3 | 0 | 3 |
| RXFP3 | TCTE1 | 0.727953 | 4 | 0 | 4 |
| RXFP3 | DEFB128 | 0.725342 | 3 | 0 | 3 |
| RXFP3 | OR2H1 | 0.723405 | 5 | 0 | 5 |
| RXFP3 | KLHDC7A | 0.722081 | 3 | 0 | 3 |
| RXFP3 | BTNL2 | 0.721705 | 7 | 0 | 7 |
| RXFP3 | ANGPT4 | 0.721303 | 7 | 0 | 7 |
For details and further investigation, click here
