| Full name: MAS related GPR family member X4 | Alias Symbol: MRGX4 | ||
| Type: protein-coding gene | Cytoband: 11p15.1 | ||
| Entrez ID: 117196 | HGNC ID: HGNC:17617 | Ensembl Gene: ENSG00000179817 | OMIM ID: 607230 |
| Drug and gene relationship at DGIdb | |||
Expression of MRGPRX4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MRGPRX4 | 117196 | 1553504_at | -0.0483 | 0.8155 | |
| GSE26886 | MRGPRX4 | 117196 | 1553504_at | 0.0646 | 0.7368 | |
| GSE45670 | MRGPRX4 | 117196 | 1553504_at | 0.0633 | 0.5022 | |
| GSE53622 | MRGPRX4 | 117196 | 96245 | 0.0117 | 0.9424 | |
| GSE53624 | MRGPRX4 | 117196 | 96245 | -0.1880 | 0.2587 | |
| GSE63941 | MRGPRX4 | 117196 | 1553504_at | 0.1169 | 0.4558 | |
| GSE77861 | MRGPRX4 | 117196 | 1553504_at | -0.0782 | 0.4057 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MRGPRX4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MRGPRX4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MRGPRX4 | 117196 | 0 | 10 | 20 | |
| GSE20123 | MRGPRX4 | 117196 | 0 | 10 | 20 | |
| GSE43470 | MRGPRX4 | 117196 | 1 | 5 | 37 | |
| GSE46452 | MRGPRX4 | 117196 | 7 | 5 | 47 | |
| GSE47630 | MRGPRX4 | 117196 | 3 | 10 | 27 | |
| GSE54993 | MRGPRX4 | 117196 | 3 | 0 | 67 | |
| GSE54994 | MRGPRX4 | 117196 | 3 | 12 | 38 | |
| GSE60625 | MRGPRX4 | 117196 | 0 | 0 | 11 | |
| GSE74703 | MRGPRX4 | 117196 | 1 | 3 | 32 | |
| GSE74704 | MRGPRX4 | 117196 | 0 | 9 | 11 | |
| TCGA | MRGPRX4 | 117196 | 11 | 29 | 56 |
Total number of gains: 29; Total number of losses: 93; Total Number of normals: 366.
Somatic mutations of MRGPRX4:
Generating mutation plots.
Highly correlated genes for MRGPRX4:
Showing top 20/67 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MRGPRX4 | SAMD15 | 0.659795 | 3 | 0 | 3 |
| MRGPRX4 | OR51M1 | 0.636422 | 4 | 0 | 3 |
| MRGPRX4 | GTPBP2 | 0.624487 | 3 | 0 | 3 |
| MRGPRX4 | G6PC2 | 0.618488 | 4 | 0 | 4 |
| MRGPRX4 | TLDC2 | 0.615948 | 5 | 0 | 5 |
| MRGPRX4 | VWA3B | 0.615206 | 3 | 0 | 3 |
| MRGPRX4 | ACTL6B | 0.607846 | 3 | 0 | 3 |
| MRGPRX4 | CASC17 | 0.607323 | 3 | 0 | 3 |
| MRGPRX4 | SLC13A3 | 0.603617 | 3 | 0 | 3 |
| MRGPRX4 | GJB1 | 0.599905 | 4 | 0 | 3 |
| MRGPRX4 | HAND1 | 0.599051 | 3 | 0 | 3 |
| MRGPRX4 | PRAMEF11 | 0.597953 | 3 | 0 | 3 |
| MRGPRX4 | LINC01007 | 0.593722 | 3 | 0 | 3 |
| MRGPRX4 | LINC00588 | 0.589179 | 4 | 0 | 3 |
| MRGPRX4 | RNF5 | 0.587303 | 3 | 0 | 3 |
| MRGPRX4 | MIR4755 | 0.586825 | 4 | 0 | 3 |
| MRGPRX4 | ALKBH3-AS1 | 0.585607 | 4 | 0 | 3 |
| MRGPRX4 | LINC00293 | 0.585506 | 3 | 0 | 3 |
| MRGPRX4 | DNAH1 | 0.585415 | 3 | 0 | 3 |
| MRGPRX4 | ERCC2 | 0.582747 | 4 | 0 | 3 |
For details and further investigation, click here
