| Full name: spermatogenesis associated 8 | Alias Symbol: MGC44294 | ||
| Type: non-coding RNA | Cytoband: 15q26.2 | ||
| Entrez ID: 145946 | HGNC ID: HGNC:28676 | Ensembl Gene: ENSG00000185594 | OMIM ID: 613948 |
| Drug and gene relationship at DGIdb | |||
Expression of SPATA8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SPATA8 | 145946 | 231006_at | 0.0603 | 0.7864 | |
| GSE26886 | SPATA8 | 145946 | 231006_at | 0.0722 | 0.6294 | |
| GSE45670 | SPATA8 | 145946 | 231006_at | 0.0524 | 0.5126 | |
| GSE53622 | SPATA8 | 145946 | 62382 | 0.1840 | 0.1427 | |
| GSE53624 | SPATA8 | 145946 | 62382 | 0.5483 | 0.0000 | |
| GSE63941 | SPATA8 | 145946 | 231006_at | 0.1690 | 0.2985 | |
| GSE77861 | SPATA8 | 145946 | 231006_at | -0.0334 | 0.7122 | |
| TCGA | SPATA8 | 145946 | RNAseq | -2.5882 | 0.0037 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by SPATA8 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SPATA8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SPATA8 | 145946 | 7 | 2 | 21 | |
| GSE20123 | SPATA8 | 145946 | 7 | 2 | 21 | |
| GSE43470 | SPATA8 | 145946 | 5 | 5 | 33 | |
| GSE46452 | SPATA8 | 145946 | 3 | 7 | 49 | |
| GSE47630 | SPATA8 | 145946 | 9 | 10 | 21 | |
| GSE54993 | SPATA8 | 145946 | 4 | 6 | 60 | |
| GSE54994 | SPATA8 | 145946 | 9 | 7 | 37 | |
| GSE60625 | SPATA8 | 145946 | 4 | 0 | 7 | |
| GSE74703 | SPATA8 | 145946 | 4 | 4 | 28 | |
| GSE74704 | SPATA8 | 145946 | 4 | 2 | 14 | |
| TCGA | SPATA8 | 145946 | 18 | 13 | 65 |
Total number of gains: 74; Total number of losses: 58; Total Number of normals: 356.
Somatic mutations of SPATA8:
Generating mutation plots.
Highly correlated genes for SPATA8:
Showing top 20/23 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SPATA8 | KIAA0754 | 0.634565 | 4 | 0 | 4 |
| SPATA8 | KIR2DS1 | 0.615227 | 4 | 0 | 4 |
| SPATA8 | LINC00652 | 0.612474 | 3 | 0 | 3 |
| SPATA8 | VWA3B | 0.611877 | 3 | 0 | 3 |
| SPATA8 | LINC00205 | 0.600808 | 3 | 0 | 3 |
| SPATA8 | SERPINA9 | 0.594354 | 3 | 0 | 3 |
| SPATA8 | SPATA24 | 0.581883 | 4 | 0 | 3 |
| SPATA8 | C11orf42 | 0.581856 | 4 | 0 | 3 |
| SPATA8 | MPV17L | 0.576154 | 4 | 0 | 3 |
| SPATA8 | FCN2 | 0.572063 | 3 | 0 | 3 |
| SPATA8 | SLC8A3 | 0.571683 | 3 | 0 | 3 |
| SPATA8 | CNGB3 | 0.563684 | 6 | 0 | 3 |
| SPATA8 | SLC17A4 | 0.560053 | 4 | 0 | 3 |
| SPATA8 | DMWD | 0.55843 | 4 | 0 | 3 |
| SPATA8 | NLRP11 | 0.546525 | 4 | 0 | 3 |
| SPATA8 | TSSK3 | 0.53959 | 4 | 0 | 3 |
| SPATA8 | LINC01312 | 0.535414 | 3 | 0 | 3 |
| SPATA8 | KIR2DL5A | 0.533642 | 4 | 0 | 3 |
| SPATA8 | C11orf72 | 0.530446 | 7 | 0 | 5 |
| SPATA8 | LINC00928 | 0.524508 | 4 | 0 | 3 |
For details and further investigation, click here
