| Full name: chromosome 8 open reading frame 74 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 8p23.1 | ||
| Entrez ID: 203076 | HGNC ID: HGNC:32296 | Ensembl Gene: ENSG00000171060 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of C8orf74:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | C8orf74 | 203076 | 1569246_a_at | -0.1619 | 0.6391 | |
| GSE26886 | C8orf74 | 203076 | 1569245_at | 0.3020 | 0.0054 | |
| GSE45670 | C8orf74 | 203076 | 1569246_a_at | 0.0065 | 0.9628 | |
| GSE53622 | C8orf74 | 203076 | 47268 | 0.4477 | 0.0069 | |
| GSE53624 | C8orf74 | 203076 | 47268 | 0.2917 | 0.0281 | |
| GSE63941 | C8orf74 | 203076 | 1569246_a_at | 0.3498 | 0.0554 | |
| GSE77861 | C8orf74 | 203076 | 1569246_a_at | -0.0973 | 0.4811 | |
| GSE97050 | C8orf74 | 203076 | A_33_P3416513 | -0.0141 | 0.9705 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by C8orf74 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of C8orf74:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | C8orf74 | 203076 | 4 | 11 | 15 | |
| GSE20123 | C8orf74 | 203076 | 4 | 11 | 15 | |
| GSE43470 | C8orf74 | 203076 | 4 | 9 | 30 | |
| GSE46452 | C8orf74 | 203076 | 12 | 14 | 33 | |
| GSE47630 | C8orf74 | 203076 | 10 | 7 | 23 | |
| GSE54993 | C8orf74 | 203076 | 3 | 14 | 53 | |
| GSE54994 | C8orf74 | 203076 | 9 | 19 | 25 | |
| GSE60625 | C8orf74 | 203076 | 3 | 0 | 8 | |
| GSE74703 | C8orf74 | 203076 | 4 | 7 | 25 | |
| GSE74704 | C8orf74 | 203076 | 3 | 7 | 10 | |
| TCGA | C8orf74 | 203076 | 13 | 40 | 43 |
Total number of gains: 69; Total number of losses: 139; Total Number of normals: 280.
Somatic mutations of C8orf74:
Generating mutation plots.
Highly correlated genes for C8orf74:
Showing top 20/320 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| C8orf74 | KRTAP10-12 | 0.796408 | 3 | 0 | 3 |
| C8orf74 | SLC39A5 | 0.786743 | 3 | 0 | 3 |
| C8orf74 | KRTAP5-7 | 0.762464 | 3 | 0 | 3 |
| C8orf74 | PLA2G2C | 0.760993 | 3 | 0 | 3 |
| C8orf74 | FOXE3 | 0.760837 | 3 | 0 | 3 |
| C8orf74 | DCDC1 | 0.760351 | 3 | 0 | 3 |
| C8orf74 | STRC | 0.757689 | 3 | 0 | 3 |
| C8orf74 | NRSN1 | 0.750254 | 3 | 0 | 3 |
| C8orf74 | ZNF763 | 0.745106 | 3 | 0 | 3 |
| C8orf74 | PDZD7 | 0.743148 | 4 | 0 | 4 |
| C8orf74 | OR2T27 | 0.739777 | 3 | 0 | 3 |
| C8orf74 | FAM71F1 | 0.736361 | 3 | 0 | 3 |
| C8orf74 | PRAMEF5 | 0.733509 | 3 | 0 | 3 |
| C8orf74 | OR2A5 | 0.726995 | 3 | 0 | 3 |
| C8orf74 | CA6 | 0.719268 | 3 | 0 | 3 |
| C8orf74 | DEFB121 | 0.712535 | 4 | 0 | 3 |
| C8orf74 | LINC00930 | 0.70751 | 5 | 0 | 5 |
| C8orf74 | TTC12 | 0.702187 | 3 | 0 | 3 |
| C8orf74 | DCAF15 | 0.698509 | 3 | 0 | 3 |
| C8orf74 | SLC26A1 | 0.696672 | 5 | 0 | 4 |
For details and further investigation, click here
