| Full name: solute carrier family 6 member 20 | Alias Symbol: XT3|Xtrp3 | ||
| Type: protein-coding gene | Cytoband: 3p21.31 | ||
| Entrez ID: 54716 | HGNC ID: HGNC:30927 | Ensembl Gene: ENSG00000163817 | OMIM ID: 605616 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC6A20:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC6A20 | 54716 | 234291_s_at | -0.0190 | 0.9498 | |
| GSE20347 | SLC6A20 | 54716 | 219614_s_at | -0.0418 | 0.6161 | |
| GSE23400 | SLC6A20 | 54716 | 219614_s_at | -0.1577 | 0.0000 | |
| GSE26886 | SLC6A20 | 54716 | 234291_s_at | 0.0978 | 0.4427 | |
| GSE29001 | SLC6A20 | 54716 | 219614_s_at | -0.0068 | 0.9685 | |
| GSE38129 | SLC6A20 | 54716 | 219614_s_at | -0.0202 | 0.7566 | |
| GSE45670 | SLC6A20 | 54716 | 234291_s_at | 0.1054 | 0.2147 | |
| GSE53622 | SLC6A20 | 54716 | 55718 | 0.7238 | 0.0157 | |
| GSE53624 | SLC6A20 | 54716 | 55718 | 0.2550 | 0.1359 | |
| GSE63941 | SLC6A20 | 54716 | 234291_s_at | 0.3875 | 0.0050 | |
| GSE77861 | SLC6A20 | 54716 | 234291_s_at | 0.0062 | 0.9700 | |
| SRP133303 | SLC6A20 | 54716 | RNAseq | 0.2053 | 0.1224 | |
| SRP159526 | SLC6A20 | 54716 | RNAseq | 1.7237 | 0.0033 | |
| SRP193095 | SLC6A20 | 54716 | RNAseq | -0.6520 | 0.0626 | |
| SRP219564 | SLC6A20 | 54716 | RNAseq | 0.6067 | 0.1146 | |
| TCGA | SLC6A20 | 54716 | RNAseq | -1.3137 | 0.0050 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by SLC6A20 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC6A20:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC6A20 | 54716 | 0 | 17 | 13 | |
| GSE20123 | SLC6A20 | 54716 | 0 | 18 | 12 | |
| GSE43470 | SLC6A20 | 54716 | 0 | 20 | 23 | |
| GSE46452 | SLC6A20 | 54716 | 2 | 17 | 40 | |
| GSE47630 | SLC6A20 | 54716 | 1 | 24 | 15 | |
| GSE54993 | SLC6A20 | 54716 | 7 | 2 | 61 | |
| GSE54994 | SLC6A20 | 54716 | 0 | 36 | 17 | |
| GSE60625 | SLC6A20 | 54716 | 5 | 0 | 6 | |
| GSE74703 | SLC6A20 | 54716 | 0 | 15 | 21 | |
| GSE74704 | SLC6A20 | 54716 | 0 | 12 | 8 | |
| TCGA | SLC6A20 | 54716 | 1 | 74 | 21 |
Total number of gains: 16; Total number of losses: 235; Total Number of normals: 237.
Somatic mutations of SLC6A20:
Generating mutation plots.
Highly correlated genes for SLC6A20:
Showing top 20/374 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC6A20 | NPB | 0.657999 | 3 | 0 | 3 |
| SLC6A20 | KRT76 | 0.655023 | 5 | 0 | 5 |
| SLC6A20 | ANXA13 | 0.650708 | 3 | 0 | 3 |
| SLC6A20 | GLRA1 | 0.648082 | 4 | 0 | 3 |
| SLC6A20 | LINC00642 | 0.64011 | 3 | 0 | 3 |
| SLC6A20 | NR2E1 | 0.637371 | 3 | 0 | 3 |
| SLC6A20 | AP2A1 | 0.630611 | 3 | 0 | 3 |
| SLC6A20 | PEX5L | 0.625906 | 5 | 0 | 4 |
| SLC6A20 | FCN2 | 0.625111 | 6 | 0 | 5 |
| SLC6A20 | CCDC71 | 0.624753 | 3 | 0 | 3 |
| SLC6A20 | USP29 | 0.622394 | 5 | 0 | 5 |
| SLC6A20 | CRB1 | 0.619282 | 4 | 0 | 3 |
| SLC6A20 | POLM | 0.616995 | 3 | 0 | 3 |
| SLC6A20 | CBLN1 | 0.616643 | 4 | 0 | 3 |
| SLC6A20 | PNOC | 0.616428 | 3 | 0 | 3 |
| SLC6A20 | SH3BP1 | 0.615737 | 6 | 0 | 5 |
| SLC6A20 | GSX2 | 0.61569 | 3 | 0 | 3 |
| SLC6A20 | DRD5 | 0.614644 | 5 | 0 | 5 |
| SLC6A20 | NEU3 | 0.612732 | 4 | 0 | 4 |
| SLC6A20 | CORO7 | 0.610238 | 3 | 0 | 3 |
For details and further investigation, click here
