ANO4

 

Full name: anoctamin 4 Alias Symbol: FLJ34221|FLJ34272|FLJ35277
Type: protein-coding gene Cytoband: 12q23.1
Entrez ID: 121601 HGNC ID: HGNC:23837 Ensembl Gene: ENSG00000151572 OMIM ID: 610111

 

Expression of ANO4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ANO4 121601 229749_at 0.0054 0.9898
GSE26886 ANO4 121601 229749_at -0.0883 0.4673
GSE45670 ANO4 121601 229749_at -0.0621 0.6327
GSE53622 ANO4 121601 126473 0.9247 0.0000
GSE53624 ANO4 121601 126473 1.4760 0.0000
GSE63941 ANO4 121601 229749_at -0.7978 0.0208
GSE77861 ANO4 121601 239883_s_at -0.0532 0.5317
TCGA ANO4 121601 RNAseq 1.8767 0.0208

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by ANO4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ANO4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ANO4 121601 2 2 26
GSE20123 ANO4 121601 2 2 26
GSE43470 ANO4 121601 2 0 41
GSE46452 ANO4 121601 9 1 49
GSE47630 ANO4 121601 9 1 30
GSE54993 ANO4 121601 0 5 65
GSE54994 ANO4 121601 4 2 47
GSE60625 ANO4 121601 0 0 11
GSE74703 ANO4 121601 2 0 34
GSE74704 ANO4 121601 1 2 17
TCGA ANO4 121601 19 10 67

Total number of gains: 50; Total number of losses: 25; Total Number of normals: 413.  

 

Somatic mutations of ANO4:

 

Generating mutation plots.

 

Highly correlated genes for ANO4:

 

Showing all 6 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ANO4CHRM20.614897303
ANO4WNT160.602711303
ANO4TTBK10.55192303
ANO4CBLN40.540649303
ANO4NAT8L0.52811403
ANO4KCTD160.514673403

For details and further investigation, click here