KCTD16

 

Full name: potassium channel tetramerization domain containing 16 Alias Symbol: KIAA1317
Type: protein-coding gene Cytoband: 5q31.3
Entrez ID: 57528 HGNC ID: HGNC:29244 Ensembl Gene: ENSG00000183775 OMIM ID: 613423
Drug and gene relationship at DGIdb

 

Expression of KCTD16:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 KCTD16 57528 233234_at -0.1330 0.5347
GSE26886 KCTD16 57528 233234_at 0.0506 0.6639
GSE45670 KCTD16 57528 233234_at 0.0369 0.6725
GSE53622 KCTD16 57528 50024 0.1213 0.2740
GSE53624 KCTD16 57528 50024 -0.2205 0.0981
GSE63941 KCTD16 57528 233234_at -1.9544 0.0000
GSE77861 KCTD16 57528 233234_at -0.1608 0.1055
SRP133303 KCTD16 57528 RNAseq 0.2197 0.5074
TCGA KCTD16 57528 RNAseq -0.2761 0.5665

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by KCTD16 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of KCTD16:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 KCTD16 57528 1 11 18
GSE20123 KCTD16 57528 1 11 18
GSE43470 KCTD16 57528 2 9 32
GSE46452 KCTD16 57528 0 27 32
GSE47630 KCTD16 57528 0 20 20
GSE54993 KCTD16 57528 9 1 60
GSE54994 KCTD16 57528 2 14 37
GSE60625 KCTD16 57528 0 0 11
GSE74703 KCTD16 57528 2 7 27
GSE74704 KCTD16 57528 1 6 13
TCGA KCTD16 57528 3 38 55

Total number of gains: 21; Total number of losses: 144; Total Number of normals: 323.  

 

Somatic mutations of KCTD16:

 

Generating mutation plots.

 

Highly correlated genes for KCTD16:

 

Showing all 15 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
KCTD16ACOX20.637437303
KCTD16LINC013980.619144303
KCTD16BRINP10.619005303
KCTD16MKRN20.61359303
KCTD16MOSPD20.61295303
KCTD16NPAS20.606073303
KCTD16KCTD60.59297303
KCTD16MAPK70.5698403
KCTD16BCAP290.539755303
KCTD16TMEM2340.523819403
KCTD16NEGR1-IT10.522859403
KCTD16WNK30.52275303
KCTD16SLC30A90.520031403
KCTD16LINC009220.516342503
KCTD16ANO40.514673403

For details and further investigation, click here