| Full name: Wnt family member 16 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 7q31.31 | ||
| Entrez ID: 51384 | HGNC ID: HGNC:16267 | Ensembl Gene: ENSG00000002745 | OMIM ID: 606267 |
| Drug and gene relationship at DGIdb | |||
WNT16 involved pathways:
Expression of WNT16:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WNT16 | 51384 | 221113_s_at | -0.1011 | 0.7558 | |
| GSE20347 | WNT16 | 51384 | 221113_s_at | -0.0675 | 0.4159 | |
| GSE23400 | WNT16 | 51384 | 221113_s_at | -0.1256 | 0.0021 | |
| GSE26886 | WNT16 | 51384 | 221113_s_at | -0.1811 | 0.1645 | |
| GSE29001 | WNT16 | 51384 | 221113_s_at | -0.0501 | 0.7970 | |
| GSE38129 | WNT16 | 51384 | 221113_s_at | 0.0044 | 0.9598 | |
| GSE45670 | WNT16 | 51384 | 221113_s_at | -0.0482 | 0.6681 | |
| GSE53622 | WNT16 | 51384 | 55863 | 0.7084 | 0.0001 | |
| GSE53624 | WNT16 | 51384 | 55863 | 1.4005 | 0.0000 | |
| GSE63941 | WNT16 | 51384 | 221113_s_at | 0.1316 | 0.6141 | |
| GSE77861 | WNT16 | 51384 | 221113_s_at | -0.2586 | 0.0333 | |
| TCGA | WNT16 | 51384 | RNAseq | 0.5019 | 0.2119 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by WNT16 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WNT16:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WNT16 | 51384 | 6 | 2 | 22 | |
| GSE20123 | WNT16 | 51384 | 7 | 2 | 21 | |
| GSE43470 | WNT16 | 51384 | 3 | 3 | 37 | |
| GSE46452 | WNT16 | 51384 | 8 | 1 | 50 | |
| GSE47630 | WNT16 | 51384 | 7 | 4 | 29 | |
| GSE54993 | WNT16 | 51384 | 2 | 6 | 62 | |
| GSE54994 | WNT16 | 51384 | 10 | 6 | 37 | |
| GSE60625 | WNT16 | 51384 | 0 | 0 | 11 | |
| GSE74703 | WNT16 | 51384 | 3 | 3 | 30 | |
| GSE74704 | WNT16 | 51384 | 5 | 2 | 13 | |
| TCGA | WNT16 | 51384 | 28 | 20 | 48 |
Total number of gains: 79; Total number of losses: 49; Total Number of normals: 360.
Somatic mutations of WNT16:
Generating mutation plots.
Highly correlated genes for WNT16:
Showing top 20/372 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WNT16 | OR6A2 | 0.740845 | 3 | 0 | 3 |
| WNT16 | APOA5 | 0.671947 | 3 | 0 | 3 |
| WNT16 | SERPINC1 | 0.667589 | 3 | 0 | 3 |
| WNT16 | DAB1 | 0.653504 | 4 | 0 | 4 |
| WNT16 | NEUROD4 | 0.650461 | 4 | 0 | 3 |
| WNT16 | VGLL2 | 0.645002 | 4 | 0 | 4 |
| WNT16 | IL1RAPL2 | 0.642476 | 4 | 0 | 4 |
| WNT16 | FGF23 | 0.64018 | 5 | 0 | 5 |
| WNT16 | MAGEC1 | 0.639729 | 3 | 0 | 3 |
| WNT16 | G6PC2 | 0.638836 | 7 | 0 | 6 |
| WNT16 | PSG6 | 0.637735 | 5 | 0 | 5 |
| WNT16 | P2RY4 | 0.636221 | 4 | 0 | 4 |
| WNT16 | CIITA | 0.6352 | 4 | 0 | 3 |
| WNT16 | GRM6 | 0.632631 | 4 | 0 | 3 |
| WNT16 | SLC45A2 | 0.632571 | 4 | 0 | 4 |
| WNT16 | IFT122 | 0.630744 | 3 | 0 | 3 |
| WNT16 | GH1 | 0.629115 | 4 | 0 | 3 |
| WNT16 | IL19 | 0.62732 | 3 | 0 | 3 |
| WNT16 | KCNC4 | 0.626396 | 3 | 0 | 3 |
| WNT16 | SERPINA6 | 0.624975 | 4 | 0 | 3 |
For details and further investigation, click here
