| Full name: N-acetyltransferase 8 like | Alias Symbol: FLJ37478|Hcml3|Shati | ||
| Type: protein-coding gene | Cytoband: 4p16.3 | ||
| Entrez ID: 339983 | HGNC ID: HGNC:26742 | Ensembl Gene: ENSG00000185818 | OMIM ID: 610647 |
| Drug and gene relationship at DGIdb | |||
Expression of NAT8L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NAT8L | 339983 | 228880_at | 0.0822 | 0.7000 | |
| GSE26886 | NAT8L | 339983 | 228880_at | 0.0807 | 0.6287 | |
| GSE45670 | NAT8L | 339983 | 228880_at | 0.1084 | 0.1376 | |
| GSE53622 | NAT8L | 339983 | 98508 | 0.8520 | 0.0005 | |
| GSE53624 | NAT8L | 339983 | 98508 | 1.9173 | 0.0000 | |
| GSE63941 | NAT8L | 339983 | 228880_at | 0.3448 | 0.2816 | |
| GSE77861 | NAT8L | 339983 | 228880_at | -0.0385 | 0.7267 | |
| GSE97050 | NAT8L | 339983 | A_33_P3670415 | -0.1695 | 0.7628 | |
| SRP159526 | NAT8L | 339983 | RNAseq | 3.6293 | 0.0004 | |
| TCGA | NAT8L | 339983 | RNAseq | -0.8459 | 0.0554 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by NAT8L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NAT8L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NAT8L | 339983 | 0 | 16 | 14 | |
| GSE20123 | NAT8L | 339983 | 0 | 16 | 14 | |
| GSE43470 | NAT8L | 339983 | 0 | 17 | 26 | |
| GSE46452 | NAT8L | 339983 | 1 | 36 | 22 | |
| GSE47630 | NAT8L | 339983 | 1 | 19 | 20 | |
| GSE54993 | NAT8L | 339983 | 11 | 0 | 59 | |
| GSE54994 | NAT8L | 339983 | 3 | 12 | 38 | |
| GSE60625 | NAT8L | 339983 | 0 | 0 | 11 | |
| GSE74703 | NAT8L | 339983 | 0 | 13 | 23 | |
| GSE74704 | NAT8L | 339983 | 0 | 8 | 12 | |
| TCGA | NAT8L | 339983 | 9 | 47 | 40 |
Total number of gains: 25; Total number of losses: 184; Total Number of normals: 279.
Somatic mutations of NAT8L:
Generating mutation plots.
Highly correlated genes for NAT8L:
Showing top 20/49 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NAT8L | F11 | 0.648636 | 3 | 0 | 3 |
| NAT8L | ARX | 0.616555 | 3 | 0 | 3 |
| NAT8L | ZNF8 | 0.610786 | 4 | 0 | 3 |
| NAT8L | DYRK3 | 0.609543 | 3 | 0 | 3 |
| NAT8L | RHPN1-AS1 | 0.607073 | 4 | 0 | 4 |
| NAT8L | ICAM5 | 0.594809 | 5 | 0 | 4 |
| NAT8L | NEUROD4 | 0.592499 | 3 | 0 | 3 |
| NAT8L | TNP2 | 0.592287 | 3 | 0 | 3 |
| NAT8L | LBX1 | 0.589811 | 3 | 0 | 3 |
| NAT8L | NDUFB11 | 0.586363 | 3 | 0 | 3 |
| NAT8L | CELA3A | 0.578635 | 3 | 0 | 3 |
| NAT8L | OR2F1 | 0.577687 | 4 | 0 | 3 |
| NAT8L | SLC32A1 | 0.575388 | 4 | 0 | 3 |
| NAT8L | TM4SF5 | 0.559443 | 3 | 0 | 3 |
| NAT8L | TOP3A | 0.556525 | 4 | 0 | 3 |
| NAT8L | ICAM1 | 0.552801 | 4 | 0 | 3 |
| NAT8L | GRIN3B | 0.551576 | 4 | 0 | 4 |
| NAT8L | CPT1C | 0.549836 | 5 | 0 | 3 |
| NAT8L | PLXNB3 | 0.54836 | 4 | 0 | 3 |
| NAT8L | ADAMTS14 | 0.546718 | 5 | 0 | 4 |
For details and further investigation, click here
