| Full name: tau tubulin kinase 1 | Alias Symbol: KIAA1855 | ||
| Type: protein-coding gene | Cytoband: 6p21.1 | ||
| Entrez ID: 84630 | HGNC ID: HGNC:19140 | Ensembl Gene: ENSG00000146216 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of TTBK1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | TTBK1 | 84630 | 230191_at | 0.0708 | 0.8624 | |
| GSE26886 | TTBK1 | 84630 | 230191_at | 0.0443 | 0.7975 | |
| GSE45670 | TTBK1 | 84630 | 230191_at | 0.0838 | 0.3374 | |
| GSE53622 | TTBK1 | 84630 | 103612 | 0.1152 | 0.1535 | |
| GSE53624 | TTBK1 | 84630 | 103612 | 0.1859 | 0.0487 | |
| GSE63941 | TTBK1 | 84630 | 230191_at | 0.2549 | 0.1430 | |
| GSE77861 | TTBK1 | 84630 | 230191_at | -0.0133 | 0.9332 | |
| GSE97050 | TTBK1 | 84630 | A_33_P3392374 | 0.0618 | 0.7578 | |
| TCGA | TTBK1 | 84630 | RNAseq | -0.0732 | 0.7972 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by TTBK1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of TTBK1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | TTBK1 | 84630 | 7 | 0 | 23 | |
| GSE20123 | TTBK1 | 84630 | 7 | 0 | 23 | |
| GSE43470 | TTBK1 | 84630 | 6 | 0 | 37 | |
| GSE46452 | TTBK1 | 84630 | 2 | 9 | 48 | |
| GSE47630 | TTBK1 | 84630 | 8 | 4 | 28 | |
| GSE54993 | TTBK1 | 84630 | 3 | 2 | 65 | |
| GSE54994 | TTBK1 | 84630 | 11 | 4 | 38 | |
| GSE60625 | TTBK1 | 84630 | 0 | 1 | 10 | |
| GSE74703 | TTBK1 | 84630 | 6 | 0 | 30 | |
| GSE74704 | TTBK1 | 84630 | 3 | 0 | 17 | |
| TCGA | TTBK1 | 84630 | 20 | 13 | 63 |
Total number of gains: 73; Total number of losses: 33; Total Number of normals: 382.
Somatic mutations of TTBK1:
Generating mutation plots.
Highly correlated genes for TTBK1:
Showing top 20/156 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| TTBK1 | NLRP5 | 0.797118 | 3 | 0 | 3 |
| TTBK1 | ZNF236 | 0.788448 | 3 | 0 | 3 |
| TTBK1 | NXNL1 | 0.766024 | 3 | 0 | 3 |
| TTBK1 | MCF2L | 0.755228 | 3 | 0 | 3 |
| TTBK1 | AOC2 | 0.742855 | 3 | 0 | 3 |
| TTBK1 | NPPA | 0.733919 | 3 | 0 | 3 |
| TTBK1 | NXPH3 | 0.726446 | 4 | 0 | 4 |
| TTBK1 | LIF | 0.713626 | 3 | 0 | 3 |
| TTBK1 | PPP2R2B | 0.706793 | 3 | 0 | 3 |
| TTBK1 | POU1F1 | 0.69763 | 3 | 0 | 3 |
| TTBK1 | TBX21 | 0.686238 | 3 | 0 | 3 |
| TTBK1 | TCTE3 | 0.685323 | 4 | 0 | 3 |
| TTBK1 | BCKDHA | 0.682979 | 3 | 0 | 3 |
| TTBK1 | PBOV1 | 0.676391 | 3 | 0 | 3 |
| TTBK1 | CCDC33 | 0.67579 | 3 | 0 | 3 |
| TTBK1 | GLP1R | 0.66621 | 4 | 0 | 4 |
| TTBK1 | SLC4A1 | 0.663933 | 4 | 0 | 3 |
| TTBK1 | MEGF11 | 0.662813 | 5 | 0 | 4 |
| TTBK1 | TCTE1 | 0.661034 | 3 | 0 | 3 |
| TTBK1 | GPR52 | 0.659033 | 5 | 0 | 4 |
For details and further investigation, click here
