C5orf49

 

Full name: chromosome 5 open reading frame 49 Alias Symbol: LOC134121
Type: protein-coding gene Cytoband: 5p15.31
Entrez ID: 134121 HGNC ID: HGNC:27028 Ensembl Gene: ENSG00000215217 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of C5orf49:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 C5orf49 134121 239722_at 0.0496 0.8193
GSE26886 C5orf49 134121 239722_at 0.0084 0.9439
GSE45670 C5orf49 134121 239722_at 0.0018 0.9874
GSE53622 C5orf49 134121 5999 0.1474 0.0697
GSE53624 C5orf49 134121 5999 0.1640 0.0658
GSE63941 C5orf49 134121 239722_at -0.0617 0.6397
GSE77861 C5orf49 134121 239722_at -0.0382 0.6922
TCGA C5orf49 134121 RNAseq -2.3006 0.0002

Upregulated datasets: 0; Downregulated datasets: 1.  

 

Survival by C5orf49 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of C5orf49:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 C5orf49 134121 12 0 18
GSE20123 C5orf49 134121 12 0 18
GSE43470 C5orf49 134121 16 0 27
GSE46452 C5orf49 134121 6 22 31
GSE47630 C5orf49 134121 6 11 23
GSE54993 C5orf49 134121 5 5 60
GSE54994 C5orf49 134121 29 1 23
GSE60625 C5orf49 134121 0 0 11
GSE74703 C5orf49 134121 12 0 24
GSE74704 C5orf49 134121 11 0 9
TCGA C5orf49 134121 57 4 35

Total number of gains: 166; Total number of losses: 43; Total Number of normals: 279.  

 

Somatic mutations of C5orf49:

 

Generating mutation plots.

 

Highly correlated genes for C5orf49:

 

Showing all 9 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
C5orf49IL210.608686303
C5orf49SLC19A30.563973403
C5orf49DMBX10.559845303
C5orf49NAT160.554565403
C5orf49ANXA2R0.55129303
C5orf49HTR5A0.53074403
C5orf49LINC012430.528647403
C5orf49LINC003170.514862503
C5orf49SPATA210.503493403

For details and further investigation, click here