SPATA21

 

Full name: spermatogenesis associated 21 Alias Symbol: spergen-2|spergen2
Type: protein-coding gene Cytoband: 1p36.13
Entrez ID: 374955 HGNC ID: HGNC:28026 Ensembl Gene: ENSG00000187144 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of SPATA21:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 SPATA21 374955 1570242_x_at -0.0191 0.9598
GSE26886 SPATA21 374955 1570241_at -0.1562 0.3572
GSE45670 SPATA21 374955 1570241_at 0.0840 0.4199
GSE53622 SPATA21 374955 160643 -0.0741 0.1493
GSE53624 SPATA21 374955 160643 -0.0570 0.6555
GSE63941 SPATA21 374955 1570241_at -0.2973 0.2202
GSE77861 SPATA21 374955 1570241_at -0.1654 0.3702
GSE97050 SPATA21 374955 A_33_P3216438 0.0521 0.7903
SRP133303 SPATA21 374955 RNAseq -0.9969 0.0005
TCGA SPATA21 374955 RNAseq 1.8825 0.2538

Upregulated datasets: 0; Downregulated datasets: 0.  


 

Survival by SPATA21 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of SPATA21:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 SPATA21 374955 1 5 24
GSE20123 SPATA21 374955 1 4 25
GSE43470 SPATA21 374955 1 8 34
GSE46452 SPATA21 374955 5 1 53
GSE47630 SPATA21 374955 8 3 29
GSE54993 SPATA21 374955 3 1 66
GSE54994 SPATA21 374955 11 4 38
GSE60625 SPATA21 374955 0 0 11
GSE74703 SPATA21 374955 1 5 30
GSE74704 SPATA21 374955 1 0 19
TCGA SPATA21 374955 11 23 62

Total number of gains: 43; Total number of losses: 54; Total Number of normals: 391.  


 

Somatic mutations of SPATA21:

 

Generating mutation plots.

 

Highly correlated genes for SPATA21:

 

Showing top 20/145 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
SPATA21PRSS360.813125303
SPATA21KRTAP19-20.744565303
SPATA21MAP40.734073303
SPATA21FIBCD10.729827303
SPATA21CFC1B0.720643303
SPATA21BCL7B0.720013303
SPATA21CHADL0.719097303
SPATA21LINC014050.706346303
SPATA21APOBR0.696302303
SPATA21RNF2240.692571303
SPATA21C1orf1670.691164303
SPATA21ADAM150.682279303
SPATA21COL11A20.67773403
SPATA21FLYWCH20.672554303
SPATA21AFTPH0.672455303
SPATA21FAM170A0.671103303
SPATA21FCHO10.669644403
SPATA21SULT1C20.667815303
SPATA21HLA-E0.667743303
SPATA21B3GNT70.659634303

For details and further investigation, click here