| Full name: solute carrier family 19 member 3 | Alias Symbol: THTR2 | ||
| Type: protein-coding gene | Cytoband: 2q36.3 | ||
| Entrez ID: 80704 | HGNC ID: HGNC:16266 | Ensembl Gene: ENSG00000135917 | OMIM ID: 606152 |
| Drug and gene relationship at DGIdb | |||
Expression of SLC19A3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SLC19A3 | 80704 | 220736_at | 0.3222 | 0.4781 | |
| GSE20347 | SLC19A3 | 80704 | 220736_at | -0.0557 | 0.3133 | |
| GSE23400 | SLC19A3 | 80704 | 220736_at | -0.1465 | 0.0001 | |
| GSE26886 | SLC19A3 | 80704 | 220736_at | -0.1612 | 0.0561 | |
| GSE29001 | SLC19A3 | 80704 | 220736_at | -0.1195 | 0.1749 | |
| GSE38129 | SLC19A3 | 80704 | 220736_at | -0.1804 | 0.0206 | |
| GSE45670 | SLC19A3 | 80704 | 220736_at | 0.1151 | 0.1994 | |
| GSE53622 | SLC19A3 | 80704 | 109172 | 0.0054 | 0.9624 | |
| GSE53624 | SLC19A3 | 80704 | 109172 | -0.0707 | 0.5839 | |
| GSE63941 | SLC19A3 | 80704 | 220736_at | 0.2657 | 0.7174 | |
| GSE77861 | SLC19A3 | 80704 | 239345_at | -0.1913 | 0.0837 | |
| GSE97050 | SLC19A3 | 80704 | A_33_P3274560 | -0.0571 | 0.8065 | |
| SRP007169 | SLC19A3 | 80704 | RNAseq | 1.2054 | 0.1635 | |
| SRP064894 | SLC19A3 | 80704 | RNAseq | 0.8894 | 0.0055 | |
| SRP133303 | SLC19A3 | 80704 | RNAseq | 0.0160 | 0.8746 | |
| SRP159526 | SLC19A3 | 80704 | RNAseq | 1.0079 | 0.0678 | |
| SRP193095 | SLC19A3 | 80704 | RNAseq | 0.0994 | 0.5482 | |
| SRP219564 | SLC19A3 | 80704 | RNAseq | 0.0678 | 0.8423 | |
| TCGA | SLC19A3 | 80704 | RNAseq | -0.3586 | 0.3781 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SLC19A3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SLC19A3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SLC19A3 | 80704 | 2 | 12 | 16 | |
| GSE20123 | SLC19A3 | 80704 | 2 | 12 | 16 | |
| GSE43470 | SLC19A3 | 80704 | 0 | 7 | 36 | |
| GSE46452 | SLC19A3 | 80704 | 0 | 5 | 54 | |
| GSE47630 | SLC19A3 | 80704 | 4 | 5 | 31 | |
| GSE54993 | SLC19A3 | 80704 | 1 | 2 | 67 | |
| GSE54994 | SLC19A3 | 80704 | 6 | 11 | 36 | |
| GSE60625 | SLC19A3 | 80704 | 0 | 3 | 8 | |
| GSE74703 | SLC19A3 | 80704 | 0 | 6 | 30 | |
| GSE74704 | SLC19A3 | 80704 | 2 | 6 | 12 | |
| TCGA | SLC19A3 | 80704 | 13 | 26 | 57 |
Total number of gains: 30; Total number of losses: 95; Total Number of normals: 363.
Somatic mutations of SLC19A3:
Generating mutation plots.
Highly correlated genes for SLC19A3:
Showing top 20/673 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SLC19A3 | YY2 | 0.880091 | 3 | 0 | 3 |
| SLC19A3 | C9orf153 | 0.834513 | 3 | 0 | 3 |
| SLC19A3 | PRSS38 | 0.834187 | 3 | 0 | 3 |
| SLC19A3 | C1QL2 | 0.797768 | 3 | 0 | 3 |
| SLC19A3 | LBX2 | 0.784749 | 3 | 0 | 3 |
| SLC19A3 | OR1J1 | 0.781856 | 3 | 0 | 3 |
| SLC19A3 | OR1J4 | 0.780172 | 4 | 0 | 4 |
| SLC19A3 | ZNF326 | 0.77949 | 3 | 0 | 3 |
| SLC19A3 | ZNF329 | 0.777795 | 3 | 0 | 3 |
| SLC19A3 | MRGPRG | 0.774602 | 3 | 0 | 3 |
| SLC19A3 | TMCC2 | 0.7722 | 3 | 0 | 3 |
| SLC19A3 | SALL3 | 0.771025 | 3 | 0 | 3 |
| SLC19A3 | DCDC1 | 0.768602 | 3 | 0 | 3 |
| SLC19A3 | GDF7 | 0.766835 | 3 | 0 | 3 |
| SLC19A3 | BBC3 | 0.762906 | 3 | 0 | 3 |
| SLC19A3 | OTOG | 0.761214 | 3 | 0 | 3 |
| SLC19A3 | MAGEA8 | 0.75693 | 3 | 0 | 3 |
| SLC19A3 | KLHL14 | 0.754066 | 3 | 0 | 3 |
| SLC19A3 | OR2D2 | 0.754022 | 3 | 0 | 3 |
| SLC19A3 | LIMD1 | 0.748282 | 3 | 0 | 3 |
For details and further investigation, click here
