CCDC158

 

Full name: coiled-coil domain containing 158 Alias Symbol: FLJ25770
Type: protein-coding gene Cytoband: 4q21.1
Entrez ID: 339965 HGNC ID: HGNC:26374 Ensembl Gene: ENSG00000163749 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of CCDC158:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CCDC158 339965 243875_at 0.0633 0.8664
GSE26886 CCDC158 339965 243875_at -0.0257 0.8453
GSE45670 CCDC158 339965 243875_at -0.0018 0.9864
GSE53622 CCDC158 339965 58580 -0.5747 0.0000
GSE53624 CCDC158 339965 58580 0.1138 0.2248
GSE63941 CCDC158 339965 243875_at -0.0054 0.9691
GSE77861 CCDC158 339965 243875_at -0.1350 0.3239
SRP133303 CCDC158 339965 RNAseq -0.5171 0.2195
TCGA CCDC158 339965 RNAseq -1.4054 0.0848

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by CCDC158 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of CCDC158:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CCDC158 339965 2 9 19
GSE20123 CCDC158 339965 2 9 19
GSE43470 CCDC158 339965 0 13 30
GSE46452 CCDC158 339965 1 36 22
GSE47630 CCDC158 339965 1 19 20
GSE54993 CCDC158 339965 7 0 63
GSE54994 CCDC158 339965 0 9 44
GSE60625 CCDC158 339965 0 0 11
GSE74703 CCDC158 339965 0 11 25
GSE74704 CCDC158 339965 2 5 13
TCGA CCDC158 339965 17 29 50

Total number of gains: 32; Total number of losses: 140; Total Number of normals: 316.  

 

Somatic mutations of CCDC158:

 

Generating mutation plots.

 

Highly correlated genes for CCDC158:

 

Showing all 9 correlated genes with mean PCC>0.5.

Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CCDC158MOS0.6124303
CCDC158ZNF5030.610431303
CCDC158SHISA80.579502404
CCDC158PRLHR0.575722303
CCDC158ZBED30.575375303
CCDC158KRTAP4-80.555599303
CCDC158LINC009430.538773403
CCDC158NFIC0.512175303
CCDC158ZNF1690.504674403

For details and further investigation, click here