| Full name: shisa family member 8 | Alias Symbol: Orf26 | ||
| Type: protein-coding gene | Cytoband: 22q13.2 | ||
| Entrez ID: 440829 | HGNC ID: HGNC:18351 | Ensembl Gene: ENSG00000234965 | OMIM ID: 617329 |
| Drug and gene relationship at DGIdb | |||
Expression of SHISA8:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SHISA8 | 440829 | 244467_at | 0.3432 | 0.5674 | |
| GSE26886 | SHISA8 | 440829 | 244467_at | 0.2051 | 0.0372 | |
| GSE45670 | SHISA8 | 440829 | 244467_at | 0.1390 | 0.1436 | |
| GSE53622 | SHISA8 | 440829 | 24097 | -0.0390 | 0.7123 | |
| GSE53624 | SHISA8 | 440829 | 24097 | -0.0238 | 0.7874 | |
| GSE63941 | SHISA8 | 440829 | 244467_at | 0.1598 | 0.5247 | |
| GSE77861 | SHISA8 | 440829 | 244467_at | -0.0312 | 0.8094 | |
| GSE97050 | SHISA8 | 440829 | A_33_P3222932 | -0.1551 | 0.6284 | |
| SRP159526 | SHISA8 | 440829 | RNAseq | 0.6061 | 0.3795 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by SHISA8 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of SHISA8:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SHISA8 | 440829 | 6 | 5 | 19 | |
| GSE20123 | SHISA8 | 440829 | 6 | 4 | 20 | |
| GSE43470 | SHISA8 | 440829 | 5 | 6 | 32 | |
| GSE46452 | SHISA8 | 440829 | 31 | 2 | 26 | |
| GSE47630 | SHISA8 | 440829 | 9 | 4 | 27 | |
| GSE54993 | SHISA8 | 440829 | 3 | 6 | 61 | |
| GSE54994 | SHISA8 | 440829 | 11 | 8 | 34 | |
| GSE60625 | SHISA8 | 440829 | 5 | 0 | 6 | |
| GSE74703 | SHISA8 | 440829 | 5 | 4 | 27 | |
| GSE74704 | SHISA8 | 440829 | 3 | 2 | 15 | |
| TCGA | SHISA8 | 440829 | 27 | 14 | 55 |
Total number of gains: 111; Total number of losses: 55; Total Number of normals: 322.
Somatic mutations of SHISA8:
Generating mutation plots.
Highly correlated genes for SHISA8:
Showing top 20/353 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SHISA8 | MOS | 0.868076 | 3 | 0 | 3 |
| SHISA8 | SLC22A7 | 0.847447 | 3 | 0 | 3 |
| SHISA8 | DCDC1 | 0.827489 | 3 | 0 | 3 |
| SHISA8 | CNOT3 | 0.81792 | 3 | 0 | 3 |
| SHISA8 | GRIK4 | 0.811257 | 3 | 0 | 3 |
| SHISA8 | NKX6-3 | 0.805369 | 3 | 0 | 3 |
| SHISA8 | GPR150 | 0.795488 | 3 | 0 | 3 |
| SHISA8 | STRC | 0.783947 | 3 | 0 | 3 |
| SHISA8 | MRGPRG | 0.783557 | 3 | 0 | 3 |
| SHISA8 | DMGDH | 0.782995 | 3 | 0 | 3 |
| SHISA8 | NPAS1 | 0.781622 | 3 | 0 | 3 |
| SHISA8 | ZNF527 | 0.779934 | 3 | 0 | 3 |
| SHISA8 | C2CD4D | 0.779301 | 3 | 0 | 3 |
| SHISA8 | YY2 | 0.77689 | 3 | 0 | 3 |
| SHISA8 | C19orf71 | 0.776498 | 3 | 0 | 3 |
| SHISA8 | SERPINA10 | 0.774124 | 3 | 0 | 3 |
| SHISA8 | ZNF157 | 0.772638 | 3 | 0 | 3 |
| SHISA8 | BBC3 | 0.769739 | 3 | 0 | 3 |
| SHISA8 | GRXCR2 | 0.757092 | 3 | 0 | 3 |
| SHISA8 | KCNK3 | 0.756562 | 4 | 0 | 3 |
For details and further investigation, click here
