ZBED3

 

Full name: zinc finger BED-type containing 3 Alias Symbol: MGC15435
Type: protein-coding gene Cytoband: 5q13.3
Entrez ID: 84327 HGNC ID: HGNC:20711 Ensembl Gene: ENSG00000132846 OMIM ID: 615250
Drug and gene relationship at DGIdb

 

Expression of ZBED3:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ZBED3 84327 228402_at -0.0781 0.9074
GSE26886 ZBED3 84327 235109_at 0.3830 0.2111
GSE45670 ZBED3 84327 235109_at -0.8632 0.0004
GSE53622 ZBED3 84327 67719 -0.4485 0.0001
GSE53624 ZBED3 84327 67719 -0.3477 0.0000
GSE63941 ZBED3 84327 228402_at 1.2478 0.0605
GSE77861 ZBED3 84327 228402_at 0.0897 0.7303
GSE97050 ZBED3 84327 A_23_P93032 -0.3972 0.2926
SRP007169 ZBED3 84327 RNAseq 0.5409 0.3286
SRP008496 ZBED3 84327 RNAseq 1.7047 0.0003
SRP064894 ZBED3 84327 RNAseq -0.0120 0.9564
SRP133303 ZBED3 84327 RNAseq -0.0493 0.7023
SRP159526 ZBED3 84327 RNAseq 0.1113 0.7671
SRP193095 ZBED3 84327 RNAseq 0.1478 0.2899
SRP219564 ZBED3 84327 RNAseq -0.0048 0.9911
TCGA ZBED3 84327 RNAseq -1.0395 0.0000

Upregulated datasets: 1; Downregulated datasets: 1.  


 

Survival by ZBED3 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of ZBED3:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ZBED3 84327 1 13 16
GSE20123 ZBED3 84327 1 13 16
GSE43470 ZBED3 84327 1 13 29
GSE46452 ZBED3 84327 0 28 31
GSE47630 ZBED3 84327 1 19 20
GSE54993 ZBED3 84327 8 1 61
GSE54994 ZBED3 84327 1 19 33
GSE60625 ZBED3 84327 0 0 11
GSE74703 ZBED3 84327 1 9 26
GSE74704 ZBED3 84327 1 6 13
TCGA ZBED3 84327 5 49 42

Total number of gains: 20; Total number of losses: 170; Total Number of normals: 298.  


 

Somatic mutations of ZBED3:

 

Generating mutation plots.

 

Highly correlated genes for ZBED3:

 

Showing top 20/222 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ZBED3FXYD10.757019303
ZBED3CORO60.685149303
ZBED3ZBTB390.674751303
ZBED3MICAL30.663665303
ZBED3SALL20.660595303
ZBED3FAM71E10.651947303
ZBED3ZNF4830.65061303
ZBED3ANKS1B0.645698404
ZBED3C11orf950.642962303
ZBED3SLC22A170.64175403
ZBED3VAMP20.63731503
ZBED3ITPK1-AS10.634864303
ZBED3SIRT10.634488303
ZBED3NUDT170.634049403
ZBED3RBM420.633029303
ZBED3RANBP3L0.631616303
ZBED3GABBR10.630731303
ZBED3MYEF20.627188403
ZBED3ZNF5810.622202303
ZBED3AATK0.619701403

For details and further investigation, click here