| Full name: nuclear factor I C | Alias Symbol: CTF|NF-I|CTF5 | ||
| Type: protein-coding gene | Cytoband: 19p13.3 | ||
| Entrez ID: 4782 | HGNC ID: HGNC:7786 | Ensembl Gene: ENSG00000141905 | OMIM ID: 600729 |
| Drug and gene relationship at DGIdb | |||
Expression of NFIC:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NFIC | 4782 | 226895_at | -0.4348 | 0.5125 | |
| GSE20347 | NFIC | 4782 | 206929_s_at | -0.5606 | 0.0000 | |
| GSE23400 | NFIC | 4782 | 206929_s_at | -0.3426 | 0.0000 | |
| GSE26886 | NFIC | 4782 | 226895_at | 0.3380 | 0.1454 | |
| GSE29001 | NFIC | 4782 | 206929_s_at | -0.2161 | 0.1872 | |
| GSE38129 | NFIC | 4782 | 206929_s_at | -0.4567 | 0.0612 | |
| GSE45670 | NFIC | 4782 | 226895_at | -0.7187 | 0.0001 | |
| GSE53622 | NFIC | 4782 | 45499 | -0.8316 | 0.0000 | |
| GSE53624 | NFIC | 4782 | 45499 | -0.5832 | 0.0000 | |
| GSE63941 | NFIC | 4782 | 226895_at | -2.1046 | 0.0002 | |
| GSE77861 | NFIC | 4782 | 226895_at | -0.2956 | 0.4437 | |
| GSE97050 | NFIC | 4782 | A_33_P3249509 | -0.6895 | 0.1194 | |
| SRP007169 | NFIC | 4782 | RNAseq | 0.4410 | 0.3406 | |
| SRP008496 | NFIC | 4782 | RNAseq | 0.5644 | 0.0639 | |
| SRP064894 | NFIC | 4782 | RNAseq | -0.1891 | 0.4571 | |
| SRP133303 | NFIC | 4782 | RNAseq | -0.6171 | 0.0018 | |
| SRP159526 | NFIC | 4782 | RNAseq | -0.3906 | 0.0886 | |
| SRP193095 | NFIC | 4782 | RNAseq | -0.2210 | 0.1748 | |
| SRP219564 | NFIC | 4782 | RNAseq | -0.2453 | 0.6355 | |
| TCGA | NFIC | 4782 | RNAseq | -0.3321 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by NFIC expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NFIC:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NFIC | 4782 | 5 | 4 | 21 | |
| GSE20123 | NFIC | 4782 | 4 | 3 | 23 | |
| GSE43470 | NFIC | 4782 | 1 | 9 | 33 | |
| GSE46452 | NFIC | 4782 | 47 | 1 | 11 | |
| GSE47630 | NFIC | 4782 | 5 | 7 | 28 | |
| GSE54993 | NFIC | 4782 | 16 | 3 | 51 | |
| GSE54994 | NFIC | 4782 | 8 | 16 | 29 | |
| GSE60625 | NFIC | 4782 | 9 | 0 | 2 | |
| GSE74703 | NFIC | 4782 | 1 | 6 | 29 | |
| GSE74704 | NFIC | 4782 | 1 | 3 | 16 | |
| TCGA | NFIC | 4782 | 10 | 19 | 67 |
Total number of gains: 107; Total number of losses: 71; Total Number of normals: 310.
Somatic mutations of NFIC:
Generating mutation plots.
Highly correlated genes for NFIC:
Showing top 20/940 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NFIC | TSHZ3 | 0.783112 | 3 | 0 | 3 |
| NFIC | LENG8 | 0.7771 | 3 | 0 | 3 |
| NFIC | AFF3 | 0.767489 | 3 | 0 | 3 |
| NFIC | DSEL | 0.763886 | 3 | 0 | 3 |
| NFIC | C20orf194 | 0.763178 | 3 | 0 | 3 |
| NFIC | ZNF521 | 0.758713 | 3 | 0 | 3 |
| NFIC | RASSF8 | 0.748219 | 3 | 0 | 3 |
| NFIC | EIF1AY | 0.736697 | 3 | 0 | 3 |
| NFIC | ENG | 0.736634 | 4 | 0 | 4 |
| NFIC | ERGIC1 | 0.722385 | 3 | 0 | 3 |
| NFIC | ARMC9 | 0.719938 | 3 | 0 | 3 |
| NFIC | UBXN1 | 0.719078 | 4 | 0 | 4 |
| NFIC | USP9Y | 0.715048 | 3 | 0 | 3 |
| NFIC | MRGPRF | 0.709978 | 5 | 0 | 4 |
| NFIC | CYTH3 | 0.709811 | 3 | 0 | 3 |
| NFIC | KDM5D | 0.709343 | 3 | 0 | 3 |
| NFIC | PIK3R1 | 0.706655 | 6 | 0 | 6 |
| NFIC | CYYR1 | 0.706471 | 3 | 0 | 3 |
| NFIC | GADD45G | 0.70255 | 6 | 0 | 5 |
| NFIC | HIC1 | 0.69964 | 4 | 0 | 3 |
For details and further investigation, click here
